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NCT02271022 · ClinicalTrials.gov registry record

Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry

A clinical trial, sponsored by AstraZeneca.

Completed
Registry status
2,000
Enrollment target

NCT02271022 is a clinical trial that has completed, run by AstraZeneca. The registered enrollment target is 2,000 participants.

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The verdict

NCT02271022 has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
2,000 participants
Enrollment target

Study Summary

The primary objective of the UPSTREAM Registry is to address the data gap regarding the course of NSTEMI (Non-ST-Elevation Myocardial Infarction)between ED (Emergency Department) arrival and diagnostic angiography in detail, by characterizing and following the ED and peri-ED use of advanced OAP (Oral Anti-Platelet) agents. In addition to exploring ED treatment patterns and success of both ischemic and bleeding risk stratification prior to definition of the coronary anatomy, data generated via the UPSTREAM registry will allow plausible attribution of ischemic and bleeding outcomes to pre-catheterization antiplatelet therapy in the management of NSTEMI. This registry further seeks to demonstrate that contemporary use of upstream ticagrelor is associated with an economically-sound utilization of hospital resources, and smooth transition of care into the outpatient, secondary prevention setting for the first 30 days after hospitalization. Finally, it will allow characterization of patient selection factors and processes for ticagrelor vs alternative OAP agents, carrying out that descriptive comparison through discharge. Patients transferred in to an UPSTREAM hospital are eligible for inclusion, but the timing for OAP agent administration and diagnostic catheterization begin with ED care at the first hospital.

Interventions

  • OTHER Non-Interventional Study

Trial Details

FieldValue
Enrollment Target 2,000 participants
Start Date 2015-02-17
Est. Completion 2019-10-31

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT02271022

The ClinicalTrials.gov registry entry for NCT02271022 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 2,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Non-Interventional Study is the first listed.

NCT02271022 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02271022 about?

NCT02271022 is a clinical study titled "Utilization of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction (UPSTREAM): An ED-Based Clinical Registry". The primary objective of the UPSTREAM Registry is to address the data gap regarding the course of NSTEMI (Non-ST-Elevation Myocardial Infarction)between ED (Emergency Department) arrival and diagnostic angiography in detail, by characterizing and following the ED and peri-ED use of advanced OAP (Ora...

What is the current status of trial NCT02271022?

This trial is currently completed. The enrollment target is 2,000 participants. The study started on 2015-02-17. Estimated completion is 2019-10-31.

What interventions are being tested in trial NCT02271022?

The interventions under investigation include: Non-Interventional Study (OTHER).

Who is sponsoring clinical trial NCT02271022?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.