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NCT02164318 · ClinicalTrials.gov registry record · NA
Effects of Exercise and Improved Nitric Oxide Bioavailability on Arteriovenous Fistula Maturation
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT02164318 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 11 participants.
The verdict
NCT02164318, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
This project will examine if enhancing Nitric Oxide (NO) bioavailability increases the rates of arteriovenous fistula (AVF) maturation in end stage renal disease patients requiring vascular access for hemodialysis. To enhance NO bioavailability the study team will utilize a program of forearm exercise training, application of nitroglycerin ointment or both. Goals of this study are (A) to measure if recruited subjects can tolerate the intervention protocols, and determine if dependent variable measures, including surgery outcome, and measurement of physiologic and biologic markers, can be obtained; (B) To measure subject compliance and adherence rates for each of the intervention arms and testing visits; (C) To examine which intervention or combination of interventions demonstrates the strongest preliminary effects in order to estimate power for a pivotal intent to treat trial; and (D) explore group differences in clinical vascular markers and biologic markers in vein tissue.
Interventions
- DRUG Nitroglycerin ointment
- OTHER Handgrip training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2014-09-01 |
| Est. Completion | 2017-03-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02164318
The ClinicalTrials.gov registry entry for NCT02164318 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Nitroglycerin ointment is the first listed.
NCT02164318 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02164318 about?
NCT02164318 is a clinical study titled "Effects of Exercise and Improved Nitric Oxide Bioavailability on Arteriovenous Fistula Maturation". This project will examine if enhancing Nitric Oxide (NO) bioavailability increases the rates of arteriovenous fistula (AVF) maturation in end stage renal disease patients requiring vascular access for hemodialysis. To enhance NO bioavailability the study team will utilize a program of forearm exerci...
What is the current status of trial NCT02164318?
This trial is currently terminated. It is a NA study. The enrollment target is 11 participants. The study started on 2014-09-01. Estimated completion is 2017-03-10.
What interventions are being tested in trial NCT02164318?
The interventions under investigation include: Nitroglycerin ointment (DRUG), Handgrip training (OTHER).
Who is sponsoring clinical trial NCT02164318?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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