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NCT02159053 · ClinicalTrials.gov registry record · Phase 3

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis

A Phase 3 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
350
Enrollment target

NCT02159053 is a Phase 3 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 350 participants.

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The verdict

NCT02159053, a Phase 3 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
350 participants
Enrollment target

Study Summary

The purpose of this study is to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, safety and tolerability up to 2 years in subjects with active AS despite current or previous NSAID, non-biologic DMARD, or biologic anti-TNFα therapy.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Secukinumab

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2015-05-18
Est. Completion 2018-01-02
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT02159053

The ClinicalTrials.gov registry entry for NCT02159053 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 350 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02159053 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02159053 about?

NCT02159053 is a clinical study titled "16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis". The purpose of this study is to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, sa...

What is the current status of trial NCT02159053?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 350 participants. The study started on 2015-05-18. Estimated completion is 2018-01-02.

What interventions are being tested in trial NCT02159053?

The interventions under investigation include: Placebo (BIOLOGICAL), Secukinumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02159053?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.