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NCT02146755 · ClinicalTrials.gov registry record
Improving Echo Measurements in the Diagnosis of Aortic Stenosis
A clinical trial of Aortic Valve Stenosis, sponsored by Baylor Research Institute.
- Completed
- Registry status
- 396
- Enrollment target
- 2
- Study locations
NCT02146755: Completed study of Aortic Valve Stenosis, sponsored by Baylor Research Institute.
NCT02146755 is a study of Aortic Valve Stenosis that has completed, run by Baylor Research Institute. The registered enrollment target is 396 participants, below the 1,030-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02146755, a study of Aortic Valve Stenosis, has completed, sponsored by Baylor Research Institute.
- COMPLETED
- Registry status
- 396 participants
- Enrollment target
- 2
- Study locations
Study Summary
Aortic stenosis is a common valvular heart disease, affecting mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. The onset of symptoms confers a poor prognosis: patients die within an average of five years after the onset of angina, three years after the onset of syncope, and two years after the onset of heart failure symptoms. The overall mortality rate is 75% at three years without surgery. Drug therapy for it remains ineffective, and aortic valve replacement is the only recommended long-term treatment.
Primary Outcome
Echocardiography assessments of Aortic stenosis are technician dependent and can vary while CT evaluations are consistent and do not vary by user. This study will retrospectively examine subjects that have undergone both assessments as a workup for definitive aortic valve treatment. The anatomical measurements obtained from CT will be used to recalculate Aortic Valve Area utilizing the standard formulas and gradients/velocities obtained from echocardiography. Patients will be reclassified approp
Conditions Studied
Study Locations (2)
Texas
- Baylor University Medical Center at Dallas - Dallas
- Heart Hospital Baylor Plano - Plano
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 396 participants |
| Start Date | 2013-08 |
| Est. Completion | 2015-12 |
What the finished NCT02146755 record still lists
NCT02146755 is an observational study that tracks outcomes without assigning an intervention. The registered 396 participants enrollment target is mid-sized for trials with a published cap, below the 1,030-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Aortic Valve Stenosis appearing as the primary indexed condition, and to 0 interventions.
NCT02146755 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02146755 about?
NCT02146755 is a clinical study titled "Improving Echo Measurements in the Diagnosis of Aortic Stenosis". Aortic stenosis is a common valvular heart disease, affecting mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. The onset of symptoms confers a poor prognosis: patients die with...
What is the current status of trial NCT02146755?
This trial is currently completed. The enrollment target is 396 participants. The study started on 2013-08. Estimated completion is 2015-12.
What conditions does trial NCT02146755 study?
This clinical trial studies the following conditions: Aortic Valve Stenosis.
Who is sponsoring clinical trial NCT02146755?
This trial is sponsored by Baylor Research Institute, which has 180 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02146755 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02146755's enrollment target sits among peer trials
396 11th of 30 higher than 20 of 30 other Aortic Valve Stenosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aortic Valve Stenosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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