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NCT02138786 · ClinicalTrials.gov registry record · Phase 2

Selinexor in Initial or Refractory and/or Relapsed Richter's Transformation

A Phase 2 study, sponsored by Karyopharm Therapeutics.

Terminated
Registry status
Phase 2
Development phase
27
Enrollment target

NCT02138786 is a Phase 2 study that was terminated before completion, run by Karyopharm Therapeutics. The registered enrollment target is 27 participants.

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The verdict

NCT02138786, a Phase 2 study, was terminated before completion, sponsored by Karyopharm Therapeutics.

TERMINATED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

This is a multi-center, phase 2, single arm, open-label study of oral selinexor monotherapy in patients with Richter's Transformation, arising in the setting of prior chronic lymphocytic leukemia (CLL), after at least one chemo-immunotherapy regimen for CLL.

Interventions

  • DRUG selinexor

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2014-11-14
Est. Completion 2016-08-31
Phase Phase 2

Sponsor

Karyopharm Therapeutics

25 total trials

What the Registry Record Tells You About NCT02138786

The ClinicalTrials.gov registry entry for NCT02138786 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Karyopharm Therapeutics, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which selinexor is the first listed.

NCT02138786 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02138786 about?

NCT02138786 is a clinical study titled "Selinexor in Initial or Refractory and/or Relapsed Richter's Transformation". This is a multi-center, phase 2, single arm, open-label study of oral selinexor monotherapy in patients with Richter's Transformation, arising in the setting of prior chronic lymphocytic leukemia (CLL), after at least one chemo-immunotherapy regimen for CLL.

What is the current status of trial NCT02138786?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2014-11-14. Estimated completion is 2016-08-31.

What interventions are being tested in trial NCT02138786?

The interventions under investigation include: selinexor (DRUG).

Who is sponsoring clinical trial NCT02138786?

This trial is sponsored by Karyopharm Therapeutics, which has 25 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.