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NCT02135705 · ClinicalTrials.gov registry record
LOWER: Lomitapide Observational Worldwide Evaluation Registry
A clinical trial of Homozygous Familial Hypercholesterolemia, sponsored by Amryt Pharma.
- Recruiting
- Registry status
- 300
- Enrollment target
- 20
- Study locations
NCT02135705 is a study of Homozygous Familial Hypercholesterolemia that is actively recruiting participants, run by Amryt Pharma. The registered enrollment target is 300 participants, above the 202-participant average among 6 other Homozygous Familial Hypercholesterolemia trials with a reported enrollment target (49% higher). The trial reports 20 study locations across 12 states.
The verdict
NCT02135705, a study of Homozygous Familial Hypercholesterolemia, is actively recruiting participants, sponsored by Amryt Pharma.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 20
- Study locations
Study Summary
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Conditions Studied
Interventions
- DRUG Lomitapide
Study Locations (20)
Arizona
- Northern Arizona Healthcare - Cottonwood
- One Medical - Gilbert
- Scottsdale Family Health - Phoenix
- Pima Heart - Tucson
Georgia
- Piedmont Heart Institute - Atlanta
- Atlanta Heart Specialists - Cumming
- Northside Hospital, Inc. - Cumming
Alabama
- Brookwood Baptist Medical Center - Birmingham
- Springhill Physician Practices - Mobile
Florida
- Preventative Cardiology, Inc. - Boca Raton
- Florida Lipid Institute - Winter Park
Indiana
- Community Health Network - Indianapolis
- St. Vincent Medical Group, Inc. - Indianapolis
Arkansas
- Arkansas Heart Center - Fort Smith
California
- Cedars-Sinai Medical Center - Los Angeles
Colorado
- University of Colorado Health - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2014-03-18 |
| Est. Completion | 2028-09-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02135705
The ClinicalTrials.gov registry entry for NCT02135705 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 202-participant average among 6 other Homozygous Familial Hypercholesterolemia trials with a reported enrollment target (49% higher). The listed sponsor is Amryt Pharma, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Homozygous Familial Hypercholesterolemia appearing as the primary indexed condition, and to 1 intervention - of which Lomitapide is the first listed.
NCT02135705 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Arizona, Georgia, Alabama.
Frequently Asked Questions
What is clinical trial NCT02135705 about?
NCT02135705 is a clinical study titled "LOWER: Lomitapide Observational Worldwide Evaluation Registry". This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
What is the current status of trial NCT02135705?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2014-03-18. Estimated completion is 2028-09-01.
What conditions does trial NCT02135705 study?
This clinical trial studies the following conditions: Homozygous Familial Hypercholesterolemia.
What interventions are being tested in trial NCT02135705?
The interventions under investigation include: Lomitapide (DRUG).
Who is sponsoring clinical trial NCT02135705?
This trial is sponsored by Amryt Pharma, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02135705 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Homozygous Familial Hypercholesterolemia
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The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
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A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)
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-
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.