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NCT01109368 · ClinicalTrials.gov registry record

The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

A clinical trial of Homozygous Familial Hypercholesterolemia, sponsored by The Rogosin Institute.

Recruiting
Registry status
60
Enrollment target
1
Study location

NCT01109368 is a study of Homozygous Familial Hypercholesterolemia that is actively recruiting participants, run by The Rogosin Institute. The registered enrollment target is 60 participants, below the 242-participant average among 6 other Homozygous Familial Hypercholesterolemia trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01109368, a study of Homozygous Familial Hypercholesterolemia, is actively recruiting participants, sponsored by The Rogosin Institute.

RECRUITING
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

This repository will establish for the first time a system to carefully assess and monitor over time the general health and the amount of cholesterol in the arteries of U.S. children and adults with homozygous familial hypercholesterolemia (hoFH). Patients with this very rare disorder have very high blood levels of cholesterol from birth due to the inheritance of an abnormal gene from each parent. As a result, if untreated, heart attacks and sudden death occur in childhood. Treatments such as LDL-apheresis and liver transplant will lower the cholesterol level, but the best treatment and the best way to monitor the effect of the treatment on the arteries are unknown. The collection of clinical data and blood for analysis of known and yet-to-be discovered markers and predictors of arterial disease will yield new information about the natural history of the disorder and response to treatment. The repository will greatly aid the development of specific protocols that seek to learn more about this disease and new therapies.

Study Locations (1)

New York

  • The Rogosin Institute, Weill Cornell Medical College - New York

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2010-06
Est. Completion 2030-05

Sponsor

The Rogosin Institute

21 total trials

What the Registry Record Tells You About NCT01109368

The ClinicalTrials.gov registry entry for NCT01109368 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 242-participant average among 6 other Homozygous Familial Hypercholesterolemia trials with a reported enrollment target (75% lower). The listed sponsor is The Rogosin Institute, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Homozygous Familial Hypercholesterolemia appearing as the primary indexed condition, and to 0 interventions.

NCT01109368 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01109368 about?

NCT01109368 is a clinical study titled "The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository". This repository will establish for the first time a system to carefully assess and monitor over time the general health and the amount of cholesterol in the arteries of U.S. children and adults with homozygous familial hypercholesterolemia (hoFH). Patients with this very rare disorder have very high...

What is the current status of trial NCT01109368?

This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2010-06. Estimated completion is 2030-05.

What conditions does trial NCT01109368 study?

This clinical trial studies the following conditions: Homozygous Familial Hypercholesterolemia.

Who is sponsoring clinical trial NCT01109368?

This trial is sponsored by The Rogosin Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01109368 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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