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NCT02111317 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects

A Phase 1 study of Healthy Subjects and Pharmacokinetics of ASP015K, sponsored by Astellas Pharma Global Development.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT02111317: Completed Phase 1 study of Healthy Subjects and Pharmacokinetics of ASP015K, sponsored by Astellas Pharma Global Development.

NCT02111317 is a Phase 1 study of Healthy Subjects and Pharmacokinetics of ASP015K that has completed, run by Astellas Pharma Global Development. The registered enrollment target is 24 participants, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02111317, a Phase 1 study of Healthy Subjects and Pharmacokinetics of ASP015K, has completed, sponsored by Astellas Pharma Global Development.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the effect of verapamil, a P-glycoprotein (P-gp) inhibitor, on the pharmacokinetics of ASP015K. This study will also assess the safety and tolerability of ASP015K administered alone and also and in combination with verapamil.

Interventions

  • DRUG verapamil
  • DRUG ASP015K

Study Locations (1)

California

  • PAREXEL - Glendale

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-10
Est. Completion 2013-11
Phase Phase 1
Astellas Pharma Global Development

168 total trials

What the finished NCT02111317 record still lists

NCT02111317 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (81% lower).

The record links to 2 conditions, with Healthy Subjects appearing as the primary indexed condition, and to 2 interventions - of which verapamil is the first listed.

NCT02111317 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT02111317 about?

NCT02111317 is a clinical study titled "A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects". The purpose of this study is to evaluate the effect of verapamil, a P-glycoprotein (P-gp) inhibitor, on the pharmacokinetics of ASP015K. This study will also assess the safety and tolerability of ASP015K administered alone and also and in combination with verapamil.

What is the current status of trial NCT02111317?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-10. Estimated completion is 2013-11.

What conditions does trial NCT02111317 study?

This clinical trial studies the following conditions: Healthy Subjects, Pharmacokinetics of ASP015K.

What interventions are being tested in trial NCT02111317?

The interventions under investigation include: verapamil (DRUG), ASP015K (DRUG).

Who is sponsoring clinical trial NCT02111317?

This trial is sponsored by Astellas Pharma Global Development, which has 168 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02111317 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Subjects

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02111317's enrollment target sits among peer trials

24 46th of 69 higher than 18 of 69 other Healthy Subjects trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Subjects trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02111317, the US trial registry maintained by the National Library of Medicine. NCT02111317 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.