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CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases
NCT02058953 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to collect and bank samples of blood and tissues (such as brain tissue or lymph nodes), as well as cerebrospinal fluid (CSF), which is the fluid that bathes and cushions the spinal cord. The investigator will analyze DNA biomarkers in the samples. The investigator hopes that by studying the biomarkers, he can develop tests in the future that can detect central nervous system (CNS) metastasis in blood samples before they show up on x-ray and develop medicines that can specifically target CNS metastasis.
Conditions Studied
Interventions
- PROCEDURE Craniotomy scheduled
- PROCEDURE Collection for non-craniotomy
Study Locations (3)
Pennsylvania
- University of Pittsburgh Medical Center- Hillman Cancer Center — Pittsburgh
Texas
- The University of Texas- MD Anderson Cancer Center — Houston
Other
- Melanoma Institute Australia- Westmead Institute for Cancer Research — Sydney
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2014-08-12 |
| Est. Completion | 2019-08-19 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02058953
The ClinicalTrials.gov registry entry for NCT02058953 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,082 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Melanoma appearing as the primary indexed condition, and to 2 interventions — of which Craniotomy scheduled is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02058953 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Pennsylvania, Texas, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02058953 about?
NCT02058953 is a clinical study titled "CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases". The purpose of this study is to collect and bank samples of blood and tissues (such as brain tissue or lymph nodes), as well as cerebrospinal fluid (CSF), which is the fluid that bathes and cushions the spinal cord. The investigator will analyze DNA biomarkers in the samples. The investigator hopes ...
What is the current status of trial NCT02058953?
This trial is currently completed. The enrollment target is 7 participants. The study started on 2014-08-12. Estimated completion is 2019-08-19.
What conditions does trial NCT02058953 study?
This clinical trial studies the following conditions: Melanoma, Brain Metastases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02058953?
The interventions under investigation include: Craniotomy scheduled (PROCEDURE), Collection for non-craniotomy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02058953?
This trial is sponsored by University of Pittsburgh, which has 1,082 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02058953 being conducted?
This trial has 3 study locations across Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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