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NCT02058953 · ClinicalTrials.gov registry record
CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases
A clinical trial of Melanoma and Brain Metastases, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 7
- Enrollment target
- 3
- Study locations
NCT02058953: Completed study of Melanoma and Brain Metastases, sponsored by University of Pittsburgh.
NCT02058953 is a study of Melanoma and Brain Metastases that has completed, run by University of Pittsburgh. The registered enrollment target is 7 participants, below the 707-participant average among 266 other Melanoma trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02058953, a study of Melanoma and Brain Metastases, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 7 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to collect and bank samples of blood and tissues (such as brain tissue or lymph nodes), as well as cerebrospinal fluid (CSF), which is the fluid that bathes and cushions the spinal cord. The investigator will analyze DNA biomarkers in the samples. The investigator hopes that by studying the biomarkers, he can develop tests in the future that can detect central nervous system (CNS) metastasis in blood samples before they show up on x-ray and develop medicines that can specifically target CNS metastasis.
Primary Outcome
Collection of these samples to help determine: if CNS melanoma metastases are similar to primary cutaneous melanomas, and assist in efforts to develop biomarkers that predict development of CNS melanoma metastases from the cutaneous primary lesion; or if CNS melanoma metastases are similar to extracranial metastases, and assist in efforts to develop effective systemic therapies for extracranial MM that also take into account the molecular profile of CNS melanoma metastases would more likely have
Conditions Studied
Interventions
- PROCEDURE Craniotomy scheduled
- PROCEDURE Collection for non-craniotomy
Study Locations (3)
Pennsylvania
- University of Pittsburgh Medical Center- Hillman Cancer Center - Pittsburgh
Texas
- The University of Texas- MD Anderson Cancer Center - Houston
Other
- Melanoma Institute Australia- Westmead Institute for Cancer Research - Sydney
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2014-08-12 |
| Est. Completion | 2019-08-19 |
What the finished NCT02058953 record still lists
NCT02058953 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 707-participant average among 266 other Melanoma trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Melanoma appearing as the primary indexed condition, and to 2 interventions - of which Craniotomy scheduled is the first listed.
NCT02058953 reports a single indexed study location in Pennsylvania, Texas, Other.
Frequently Asked Questions
What is clinical trial NCT02058953 about?
NCT02058953 is a clinical study titled "CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases". The purpose of this study is to collect and bank samples of blood and tissues (such as brain tissue or lymph nodes), as well as cerebrospinal fluid (CSF), which is the fluid that bathes and cushions the spinal cord. The investigator will analyze DNA biomarkers in the samples. The investigator hopes ...
What is the current status of trial NCT02058953?
This trial is currently completed. The enrollment target is 7 participants. The study started on 2014-08-12. Estimated completion is 2019-08-19.
What conditions does trial NCT02058953 study?
This clinical trial studies the following conditions: Melanoma, Brain Metastases.
What interventions are being tested in trial NCT02058953?
The interventions under investigation include: Craniotomy scheduled (PROCEDURE), Collection for non-craniotomy (PROCEDURE).
Who is sponsoring clinical trial NCT02058953?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02058953 being conducted?
This trial has 3 study locations across Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Melanoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02058953's enrollment target sits among peer trials
7 258th of 266 higher than 7 of 266 other Melanoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Melanoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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