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NCT02049268 · ClinicalTrials.gov registry record · NA
Neural Mechanisms Underlying Nicotine and Alcohol Combinations
A NA study of Focus: Effects of Nicotine and Alcohol on Brain Circuits, sponsored by Mclean Hospital.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT02049268 is a NA study of Focus: Effects of Nicotine and Alcohol on Brain Circuits that has completed, run by Mclean Hospital. The registered enrollment target is 12 participants. The trial reports 1 study location across 1 state.
The verdict
NCT02049268, a NA study of Focus: Effects of Nicotine and Alcohol on Brain Circuits, has completed, sponsored by Mclean Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Nicotine and alcohol are frequently used together and their combined use contributes to more than half a million deaths each year, with more alcoholics dying from smoking-related diseases than from alcohol-related diseases. Using a new multi-modal MRI approach combined with data fusion, the investigators propose to study how nicotine modulates alcohol-induced changes in the function of brain circuits. The investigators hypotheses are: * functional connectivity (FC) in the reward network, containing components of the mesolimbic dopamine system, will be altered by alcohol, and additional increases in FC will be observed if nicotine is also present (e.g., additive effects). * co-administration of nicotine will counteract the effects of alcohol on FC in multiple brain networks, including visual, sensorimotor and motor brain circuits, that may be associated with the impairing effects of alcohol
Conditions Studied
Interventions
- DRUG Nicotine + Alcohol
- DRUG Placebo Nicotine + Alcohol
- DRUG Nicotine + Placebo Alcohol
Study Locations (1)
Massachusetts
- McLean Hospital - Belmont
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2013-07 |
| Est. Completion | 2015-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02049268
The ClinicalTrials.gov registry entry for NCT02049268 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mclean Hospital, which has 140 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Focus: Effects of Nicotine and Alcohol on Brain Circuits appearing as the primary indexed condition, and to 3 interventions - of which Nicotine + Alcohol is the first listed.
NCT02049268 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02049268 about?
NCT02049268 is a clinical study titled "Neural Mechanisms Underlying Nicotine and Alcohol Combinations". Nicotine and alcohol are frequently used together and their combined use contributes to more than half a million deaths each year, with more alcoholics dying from smoking-related diseases than from alcohol-related diseases. Using a new multi-modal MRI approach combined with data fusion, the investig...
What is the current status of trial NCT02049268?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2013-07. Estimated completion is 2015-12.
What conditions does trial NCT02049268 study?
This clinical trial studies the following conditions: Focus: Effects of Nicotine and Alcohol on Brain Circuits.
What interventions are being tested in trial NCT02049268?
The interventions under investigation include: Nicotine + Alcohol (DRUG), Placebo Nicotine + Alcohol (DRUG), Nicotine + Placebo Alcohol (DRUG).
Who is sponsoring clinical trial NCT02049268?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02049268 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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