Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02026960 · ClinicalTrials.gov registry record · NA

RNA Extraction and Amplification From Biopsy Specimens in Subjects With Metastatic Renal Cell Carcinoma (AGS-NTS-017)

A NA study, sponsored by Duke University.

Terminated
Registry status
NA
Development phase
14
Enrollment target

NCT02026960: Clinical Trial NA study, sponsored by Duke University.

NCT02026960 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02026960, a NA study, was terminated before completion, sponsored by Duke University.

TERMINATED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

The primary objective is to evaluate methods for AGS-003 production from surgical (stage I) and metastatic biopsy (stage II) Renal Cell Carcinoma (RCC) and a small subset of other GU cancers (expansion cohort) specimens using core needle biopsy in subjects with RCC or other GU cancers. Specifically, this study will evaluate the feasibility of RNA amplification from total tumor RNA isolated from tissues obtained by core needle tumor biopsy.

Primary Outcome

To Determine the success rate for tumor RNA isolation and amplification create a minimum of 10 doses of AGS-003, as defined by a minimum concentration of ≥84 µg/µL in typically greater than 150 µL final volume RNA. (Tissue obtained at time of surgery or biopsy depending on stage)

Interventions

  • DEVICE RNA extraction and amplification from biopsy specimens

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2014-03
Est. Completion 2017-09-07
Phase NA
Duke University

1,725 total trials

Why NCT02026960 stopped before completion

NCT02026960 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which RNA extraction and amplification from biopsy specimens is the first listed.

NCT02026960 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02026960 about?

NCT02026960 is a clinical study titled "RNA Extraction and Amplification From Biopsy Specimens in Subjects With Metastatic Renal Cell Carcinoma (AGS-NTS-017)". The primary objective is to evaluate methods for AGS-003 production from surgical (stage I) and metastatic biopsy (stage II) Renal Cell Carcinoma (RCC) and a small subset of other GU cancers (expansion cohort) specimens using core needle biopsy in subjects with RCC or other GU cancers. Specifically,...

What is the current status of trial NCT02026960?

This trial is currently terminated. It is a NA study. The enrollment target is 14 participants. The study started on 2014-03. Estimated completion is 2017-09-07.

What interventions are being tested in trial NCT02026960?

The interventions under investigation include: RNA extraction and amplification from biopsy specimens (DEVICE).

Who is sponsoring clinical trial NCT02026960?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02026960's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02523092 · 14 participants · Phase 4

    Use of CXCL9 as a Biomarker of Acthar Efficacy

  • NCT04263285 · 14 participants · NA

    Treatment of Depression Post-SCI

  • NCT04743271 · 14 participants · NA

    Food and Circadian Timing

  • NCT05065671 · 14 participants · Phase 1

    Microbiome Derived Metabolism and Pharmacokinetics

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02026960, the US trial registry maintained by the National Library of Medicine. NCT02026960 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.