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NCT02019355 · ClinicalTrials.gov registry record · Early Phase 1
Actinic Keratosis Study
A Early Phase 1 study of Actinic Keratosis, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 132
- Enrollment target
- 1
- Study location
NCT02019355: Completed Early Phase 1 study of Actinic Keratosis, sponsored by Washington University School of Medicine.
NCT02019355 is a Early Phase 1 study of Actinic Keratosis that has completed, run by Washington University School of Medicine. The registered enrollment target is 132 participants, below the 181-participant average among 16 other Actinic Keratosis trials with a reported enrollment target (27% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02019355, a Early Phase 1 study of Actinic Keratosis, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 132 participants
- Enrollment target
- 1
- Study location
Study Summary
The main purpose of this study is to determine the effectiveness of a new combination therapy for actinic keratosis. This study investigates a new indication for an FDA-approved topical medication, calcipotriol, for treatment of actinic keratosis, including how well it works and how safe it is when used in combination with the standard of care medication (5-fluorouracil) for the skin condition.
Primary Outcome
To compare the efficacy of topical 5-fluorouracil+calcipotriol vs. 5-fluorouracil alone in treatment of actinic keratosis in patients with multiple actinic keratoses at each of the four anatomical sites (scalp, face, right upper extremity and left upper extremity). The outcome of interest is percentage change from baseline number of actinic keratoses in the target treatment area on scalp, face, right upper extremity and left upper extremity at 8 weeks after treatment.
Conditions Studied
Interventions
- DRUG Vaseline
- DRUG 5-fluorouracil 5% cream
- DRUG Calcipotriol 0.005% ointment
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2013-10 |
| Est. Completion | 2015-03 |
| Phase | Early Phase 1 |
What the finished NCT02019355 record still lists
NCT02019355 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 181-participant average among 16 other Actinic Keratosis trials with a reported enrollment target (27% lower).
The record links to 1 condition, with Actinic Keratosis appearing as the primary indexed condition, and to 3 interventions - of which Vaseline is the first listed.
NCT02019355 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT02019355 about?
NCT02019355 is a clinical study titled "Actinic Keratosis Study". The main purpose of this study is to determine the effectiveness of a new combination therapy for actinic keratosis. This study investigates a new indication for an FDA-approved topical medication, calcipotriol, for treatment of actinic keratosis, including how well it works and how safe it is when ...
What is the current status of trial NCT02019355?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 132 participants. The study started on 2013-10. Estimated completion is 2015-03.
What conditions does trial NCT02019355 study?
This clinical trial studies the following conditions: Actinic Keratosis.
What interventions are being tested in trial NCT02019355?
The interventions under investigation include: Vaseline (DRUG), 5-fluorouracil 5% cream (DRUG), Calcipotriol 0.005% ointment (DRUG).
Who is sponsoring clinical trial NCT02019355?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02019355 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Actinic Keratosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02019355's enrollment target sits among peer trials
132 7th of 16 higher than 10 of 16 other Actinic Keratosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Actinic Keratosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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