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NCT01992679 · ClinicalTrials.gov registry record · Phase 1

Body Weight Supported Treadmill Training in Persons With Multiple Sclerosis

A Phase 1 study of Multiple Sclerosis, sponsored by University of Illinois at Urbana-Champaign.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT01992679 is a Phase 1 study of Multiple Sclerosis that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 24 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01992679, a Phase 1 study of Multiple Sclerosis, has completed, sponsored by University of Illinois at Urbana-Champaign.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

There is growing evidence that exercise-based rehabilitation results in improvements in mobility and participation in persons with multiple sclerosis (MS). However, the vast majority of the scientific evidence in support of this view is based on persons with MS who have minimal mobility impairment. This is partially due to the lack of accessible exercise equipment and facilities available to persons with severe mobility limitations. One option available to persons with severe mobility limitations is body weight supported treadmill training. Indeed, this rehabilitation approach has been utilized with some success in various clinical populations, such as stroke and spinal cord injury, and is believed to target neuroplasticity. Specific to persons with MS, body weight supported treadmill training has shown great promise in improving quality of life, symptoms and functional mobility in two small (n=4 and n=6) pilot investigations. However, previous research has been hampered by methodological limitations including small sample size, lack of a control group and limited training sessions. Consequently, no firm conclusion regarding the benefit of body weighted supported treadmill training in persons with MS can be drawn. The proposed project seeks to determine if twenty-weeks of body weight supported treadmill training leads to improvements in physiological function, mobility and quality of life in persons with MS with severe mobility limitations. The outcomes of this project have the potential to lead to new rehabilitation approaches capable of improving function and quality of life in persons with advanced MS.

Conditions Studied

Interventions

  • BEHAVIORAL Exercise group

Study Locations (1)

Illinois

  • University of Illinois UC - Urbana-Champaign

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-10
Est. Completion 2014-09
Phase Phase 1

What the Registry Record Tells You About NCT01992679

The ClinicalTrials.gov registry entry for NCT01992679 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower). The listed sponsor is University of Illinois at Urbana-Champaign, which has 129 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Exercise group is the first listed.

NCT01992679 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT01992679 about?

NCT01992679 is a clinical study titled "Body Weight Supported Treadmill Training in Persons With Multiple Sclerosis". There is growing evidence that exercise-based rehabilitation results in improvements in mobility and participation in persons with multiple sclerosis (MS). However, the vast majority of the scientific evidence in support of this view is based on persons with MS who have minimal mobility impairment. ...

What is the current status of trial NCT01992679?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-10. Estimated completion is 2014-09.

What conditions does trial NCT01992679 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT01992679?

The interventions under investigation include: Exercise group (BEHAVIORAL).

Who is sponsoring clinical trial NCT01992679?

This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01992679 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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