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NCT01992679 · ClinicalTrials.gov registry record · Phase 1
Body Weight Supported Treadmill Training in Persons With Multiple Sclerosis
A Phase 1 study of Multiple Sclerosis, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT01992679: Completed Phase 1 study of Multiple Sclerosis, sponsored by University of Illinois at Urbana-Champaign.
NCT01992679 is a Phase 1 study of Multiple Sclerosis that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 24 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01992679, a Phase 1 study of Multiple Sclerosis, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
There is growing evidence that exercise-based rehabilitation results in improvements in mobility and participation in persons with multiple sclerosis (MS). However, the vast majority of the scientific evidence in support of this view is based on persons with MS who have minimal mobility impairment. This is partially due to the lack of accessible exercise equipment and facilities available to persons with severe mobility limitations. One option available to persons with severe mobility limitations is body weight supported treadmill training. Indeed, this rehabilitation approach has been utilized with some success in various clinical populations, such as stroke and spinal cord injury, and is believed to target neuroplasticity. Specific to persons with MS, body weight supported treadmill training has shown great promise in improving quality of life, symptoms and functional mobility in two small (n=4 and n=6) pilot investigations. However, previous research has been hampered by methodological limitations including small sample size, lack of a control group and limited training sessions. Consequently, no firm conclusion regarding the benefit of body weighted supported treadmill training in persons with MS can be drawn. The proposed project seeks to determine if twenty-weeks of body weight supported treadmill training leads to improvements in physiological function, mobility and quality of life in persons with MS with severe mobility limitations. The outcomes of this project have the potential to lead to new rehabilitation approaches capable of improving function and quality of life in persons with advanced MS.
Primary Outcome
Clinical disability will be indexed by expanded disability status scale.
Conditions Studied
Interventions
- BEHAVIORAL Exercise group
Study Locations (1)
Illinois
- University of Illinois UC - Urbana-Champaign
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2013-10 |
| Est. Completion | 2014-09 |
| Phase | Phase 1 |
What the finished NCT01992679 record still lists
NCT01992679 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Exercise group is the first listed.
NCT01992679 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01992679 about?
NCT01992679 is a clinical study titled "Body Weight Supported Treadmill Training in Persons With Multiple Sclerosis". There is growing evidence that exercise-based rehabilitation results in improvements in mobility and participation in persons with multiple sclerosis (MS). However, the vast majority of the scientific evidence in support of this view is based on persons with MS who have minimal mobility impairment. ...
What is the current status of trial NCT01992679?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-10. Estimated completion is 2014-09.
What conditions does trial NCT01992679 study?
This clinical trial studies the following conditions: Multiple Sclerosis.
What interventions are being tested in trial NCT01992679?
The interventions under investigation include: Exercise group (BEHAVIORAL).
Who is sponsoring clinical trial NCT01992679?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01992679 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01992679's enrollment target sits among peer trials
24 246th of 315 higher than 63 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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