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NCT01883167 · ClinicalTrials.gov registry record · Phase 1

RDEA3170 and Febuxostat Drug Interaction Study

A Phase 1 study, sponsored by Ardea Biosciences.

Completed
Registry status
Phase 1
Development phase
21
Enrollment target

NCT01883167 is a Phase 1 study that has completed, run by Ardea Biosciences. The registered enrollment target is 21 participants.

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The verdict

NCT01883167, a Phase 1 study, has completed, sponsored by Ardea Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
21 participants
Enrollment target

Study Summary

This study will evaluate the potential pharmacokinetic (PK) and pharmacodynamic (PD) interaction between the XO inhibitor febuxostat and the investigational URAT1 inhibitor RDEA3170 and provide information for potential future clinical studies using this combination. Combination treatment using 2 drugs with different mechanisms of action may achieve improved response and may allow the use of lower doses, resulting in fewer side effects than the use of either drug alone.

Interventions

  • DRUG placebo
  • DRUG RDEA3170 10 mg
  • DRUG Febuxostat 40 mg

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2013-06
Est. Completion 2013-12
Phase Phase 1

Sponsor

Ardea Biosciences

32 total trials

What the Registry Record Tells You About NCT01883167

The ClinicalTrials.gov registry entry for NCT01883167 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ardea Biosciences, which has 32 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.

NCT01883167 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01883167 about?

NCT01883167 is a clinical study titled "RDEA3170 and Febuxostat Drug Interaction Study". This study will evaluate the potential pharmacokinetic (PK) and pharmacodynamic (PD) interaction between the XO inhibitor febuxostat and the investigational URAT1 inhibitor RDEA3170 and provide information for potential future clinical studies using this combination. Combination treatment using 2 dr...

What is the current status of trial NCT01883167?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2013-06. Estimated completion is 2013-12.

What interventions are being tested in trial NCT01883167?

The interventions under investigation include: placebo (DRUG), RDEA3170 10 mg (DRUG), Febuxostat 40 mg (DRUG).

Who is sponsoring clinical trial NCT01883167?

This trial is sponsored by Ardea Biosciences, which has 32 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.