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NCT01878019 · ClinicalTrials.gov registry record
Brain Response to Pain Control in People With Chronic Pain
A clinical trial of Pain, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- Completed
- Registry status
- 92
- Enrollment target
- 1
- Study location
NCT01878019: Completed study of Pain, sponsored by National Center for Complementary and Integrative Health (NCCIH).
NCT01878019 is a study of Pain that has completed, run by National Center for Complementary and Integrative Health (NCCIH). The registered enrollment target is 92 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01878019, a study of Pain, has completed, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- COMPLETED
- Registry status
- 92 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Researchers want to look at how the brain responds to painful stimulations. They also want to see if these responses are different in people with and without chronic pain. To test the brain s response, they will use a chemical called naloxone. Naloxone is used to treat overdoses of painkilling drugs like morphine. It may be able to block the effect of a pain-relieving cream. Researchers will apply a pain-relieving cream to a person s lower leg and look at the results of sensitivity tests with either naloxone or a placebo. This study will compare the results from people with chronic pain (like fibromyalgia) to those of people without chronic pain. Objectives: \- To look at the brain s response to pain in people with and without chronic pain. Eligibility: * Individuals at least 18 years of age who have fibromyalgia. * Healthy volunteers at least 18 years of age. Design: * This study will involve a screening visit and two testing visits. The testing visits will be about a week apart. * Participants will be screened with a physical exam and medical history. Blood and urine samples will be collected. After the screening participants will be administered several questionnaires about their personality, and their thoughts and feelings. * At the first visit, participants will try out the magnetic resonance imaging (MRI) scan before using it at the next visit. They will then have the painkilling cream applied on one part of their lower leg and a normal moisturizing cream on the other part of their lower leg. They will have heat pulses on these skin areas and rate the pain. * At the second visit, participants will have tests in the MRI scanner. The heat pulse tests will be repeated after an infusion of either naloxone or a placebo.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2013-05-28 |
| Est. Completion | 2016-09-08 |
What the finished NCT01878019 record still lists
NCT01878019 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (70% lower).
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 0 interventions.
NCT01878019 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01878019 about?
NCT01878019 is a clinical study titled "Brain Response to Pain Control in People With Chronic Pain". Background: \- Researchers want to look at how the brain responds to painful stimulations. They also want to see if these responses are different in people with and without chronic pain. To test the brain s response, they will use a chemical called naloxone. Naloxone is used to treat overdoses of p...
What is the current status of trial NCT01878019?
This trial is currently completed. The enrollment target is 92 participants. The study started on 2013-05-28. Estimated completion is 2016-09-08.
What conditions does trial NCT01878019 study?
This clinical trial studies the following conditions: Pain.
Who is sponsoring clinical trial NCT01878019?
This trial is sponsored by National Center for Complementary and Integrative Health (NCCIH), which has 203 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01878019 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01878019's enrollment target sits among peer trials
92 180th of 374 higher than 195 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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