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NCT01876368 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan

A Phase 3 study of Hypertension, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
376
Enrollment target
20
Study locations

NCT01876368 is a Phase 3 study of Hypertension that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 376 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (89% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT01876368, a Phase 3 study of Hypertension, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
376 participants
Enrollment target
20
Study locations

Study Summary

This study will assess the efficacy and safety of LCZ696 in comparison to olmesartan in essential hypertensive patients not adequately responsive to olmesartan

Conditions Studied

Interventions

  • DRUG LCZ696
  • DRUG Olmesartan
  • DRUG Placebo of LCZ696
  • DRUG Placebo of Olmesartan

Study Locations (20)

California

  • Novartis Investigative Site - Fair Oaks
  • Novartis Investigative Site - Hawaiian Gardens
  • Novartis Investigative Site - Long Beach
  • Novartis Investigative Site - Los Angeles
  • Novartis Investigative Site - Orangevale
  • Novartis Investigative Site - Westlake Village

Georgia

  • Novartis Investigative Site - Atlanta
  • Novartis Investigative Site - Conyers

Illinois

  • Novartis Investigative Site - Chicago
  • Novartis Investigative Site - Chicago

Mississippi

  • Novartis Investigative Site - Belzoni
  • Novartis Investigative Site - Jackson

Oregon

  • Novartis Investigative Site - Oregon City
  • Novartis Investigative Site - Portland

Alabama

  • Novartis Investigative Site - Birmingham

Colorado

  • Novartis Investigative Site - Denver

Kansas

  • Novartis Investigative Site - Topeka

Trial Details

FieldValue
Enrollment Target 376 participants
Start Date 2013-09
Est. Completion 2014-08
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT01876368

The ClinicalTrials.gov registry entry for NCT01876368 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 376 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (89% lower). The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hypertension appearing as the primary indexed condition, and to 4 interventions - of which LCZ696 is the first listed.

NCT01876368 reports 20 study locations spanning 11 distinct geographic areas - top geographies include California, Georgia, Illinois.

Frequently Asked Questions

What is clinical trial NCT01876368 about?

NCT01876368 is a clinical study titled "Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan". This study will assess the efficacy and safety of LCZ696 in comparison to olmesartan in essential hypertensive patients not adequately responsive to olmesartan

What is the current status of trial NCT01876368?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 376 participants. The study started on 2013-09. Estimated completion is 2014-08.

What conditions does trial NCT01876368 study?

This clinical trial studies the following conditions: Hypertension.

What interventions are being tested in trial NCT01876368?

The interventions under investigation include: LCZ696 (DRUG), Olmesartan (DRUG), Placebo of LCZ696 (DRUG), Placebo of Olmesartan (DRUG).

Who is sponsoring clinical trial NCT01876368?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01876368 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.