Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Open-Label Study Evaluating Dasatinib Therapy Discontinuation in Patients With Chronic Phase Chronic Myeloid Leukemia With Stable Complete Molecular Response
NCT01850004 · View on ClinicalTrials.gov ↗
Study Summary
The study purpose is to test the hypothesis that Chronic Phase Chronic Myeloid Leukemia (CP-CML) patients with stable Complete Molecular Response (CMR) who discontinue Dasatinib treatment are able to maintain a sustained remission in the long-term, with undetectable or minimally detectable BCR-ABL residual disease.
Conditions Studied
Interventions
- DRUG Dasatinib
Study Locations (20)
Other
- Local Institution - 0012 — Paris
- Local Institution - 0003 — Pessac
- Local Institution - 0030 — Pierre-Bénite
- Local Institution - 0002 — Vandœuvre-lès-Nancy
- Local Institution - 0026 — Aachen
- Local Institution - 0020 — Berlin
- Local Institution - 0021 — Mannheim
- Local Institution - 0022 — Ulm
- Local Institution - 0025 — Catania
- Local Institution - 0017 — Florence
California
- Local Institution - 0006 — Duarte
- Local Institution - 0029 — Los Angeles
- Local Institution - 0001 — San Franisco
Texas
- Local Institution - 0011 — Dallas
- Local Institution - 0023 — Houston
Illinois
- Local Institution - 0013 — Chicago
New Jersey
- Local Institution - 0024 — Hackensack
New York
- Local Institution - 0028 — New York
Ontario
- Local Institution - 0005 — Toronto
Mecklenburg-Vorpommern
- Local Institution - 0019 — Rostock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2014-01-22 |
| Est. Completion | 2021-10-08 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01850004
The ClinicalTrials.gov registry entry for NCT01850004 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 504 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Chronic Phase Chronic Myeloid Leukemia appearing as the primary indexed condition, and to 1 intervention — of which Dasatinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01850004 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Other, California, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01850004 about?
NCT01850004 is a clinical study titled "Open-Label Study Evaluating Dasatinib Therapy Discontinuation in Patients With Chronic Phase Chronic Myeloid Leukemia With Stable Complete Molecular Response". The study purpose is to test the hypothesis that Chronic Phase Chronic Myeloid Leukemia (CP-CML) patients with stable Complete Molecular Response (CMR) who discontinue Dasatinib treatment are able to maintain a sustained remission in the long-term, with undetectable or minimally detectable BCR-ABL r...
What is the current status of trial NCT01850004?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2014-01-22. Estimated completion is 2021-10-08.
What conditions does trial NCT01850004 study?
This clinical trial studies the following conditions: Chronic Phase Chronic Myeloid Leukemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01850004?
The interventions under investigation include: Dasatinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01850004?
This trial is sponsored by Bristol-Myers Squibb, which has 504 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01850004 being conducted?
This trial has 20 study locations across California, Illinois, New Jersey, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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