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ClinicalTrials.gov 2 recruiting now small index

Trisomy 21 clinical trials

2 of 6 indexed Trisomy 21 trials are currently recruiting.

Corpus placement: #2,866 of 28,707 conditions by registered trial count.

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6 US clinical trials · 2 currently recruiting · #2,866 of 28,707 conditions by registered trial count

Trisomy 21: 6 US clinical trials tracked, 2 recruiting.

Trisomy 21 is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. The most active sponsor is Natera, running 3 of these trials.

Enrollment posture brief

Registry condition trisomy-21

OPEN 2 | RECR 33% | LATE 0 | EARLY 0 | RANK #2866 | SPON 3

Volume-matched condition peers

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Acute Hypoxemic Respiratory 66.7%Abdominal Aortic Aneurysms50%Acupuncture50%Acute Lymphoblastic Leukemia50%Trisomy 21 (this)33%
Open-enrollment share among volume-matched conditions near Trisomy 21

Trisomy 21 lists 2 open slots (33% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Trisomy 21 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Trisomy 21 is recruiting below its size-band peers.

    2 of 6 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Trisomy 21 research.

    Natera accounts for 3 of 6 trials (50%). 4 distinct sponsors appear on at least one study for this condition label.

  3. Typical Trisomy 21 enrolment sits around 354 participants.

    Median target enrolment is 354 among the 6 trials that report a genuine target (sentinel values excluded). 1 of those (16.7%) plan for fewer than 100 participants.

  4. Trisomy 21 research leans observational.

    1 interventional and 5 observational studies make up this index (16.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase Distribution

Phase data not available

Top Sponsors

Natera 3 trials
University of Colorado, Denver 1 trials
University of Michigan 1 trials
Children's Hospital of Philadelphia 1 trials

Named interventions

Most-linked intervention names on Trisomy 21 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Self-Supporting Nasopharyngeal Airway (ssNPA) Device
1 trials

US sites by state

Facility locations filed on Trisomy 21 trials. A trial with sites in several states counts in each.

Pennsylvania 3 trials
New York 3 trials
California 3 trials
Texas 2 trials
New Jersey 2 trials
Michigan 2 trials
District of Columbia 2 trials
Colorado 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Trisomy 21 page

6 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Trisomy 21 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Natera sponsors the most Trisomy 21 trials on record, review their full trial history before evaluating a specific study. See Natera's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Trisomy 21 condition card totals 6 registered trials; most-linked intervention Self-Supporting Nasopharyngeal Airway (ssNPA); top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.