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NCT01674140 · ClinicalTrials.gov registry record · Phase 3
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
A Phase 3 study of Breast Cancer, sponsored by SWOG Cancer Research Network.
- Active
- Registry status
- Phase 3
- Development phase
- 1,939
- Enrollment target
- 20
- Study locations
NCT01674140: Active Phase 3 study of Breast Cancer, sponsored by SWOG Cancer Research Network.
NCT01674140 is a Phase 3 study of Breast Cancer that is active but no longer recruiting, run by SWOG Cancer Research Network. The registered enrollment target is 1,939 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (31% lower). The trial reports 20 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01674140, a Phase 3 study of Breast Cancer, is active but no longer recruiting, sponsored by SWOG Cancer Research Network.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,939 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate, goserelin acetate, leuprolide acetate, anastrozole, letrozole, or exemestane, may fight breast cancer by lowering the amount of estrogen the body makes. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet know whether hormone therapy is more effective when given with or without everolimus in treating breast cancer. PURPOSE: This randomized phase III trial studies how well giving hormone therapy together with or without everolimus work in treating patients with breast cancer.
Primary Outcome
Time from date of registration to date of first invasive recurrence (local, regional or distant), second invasive primary cancer (breast or not), or death due to any cause. Patients last known to be alive who have not experienced recurrence or second primary cancer are censored at their last contact date. The results were presented as 5-year IDFS estimate.
Conditions Studied
Interventions
- DRUG letrozole
- DRUG everolimus
- DRUG anastrozole
- DRUG exemestane
- DRUG goserelin acetate
Study Locations (20)
Alaska
- Anchorage Associates in Radiation Medicine - Anchorage
- Anchorage Radiation Therapy Center - Anchorage
- Alaska Breast Care and Surgery LLC - Anchorage
- Alaska Oncology and Hematology LLC - Anchorage
- Alaska Regional Hospital - Anchorage
- Alaska Women's Cancer Care - Anchorage
- Anchorage Oncology Centre - Anchorage
- Katmai Oncology Group - Anchorage
- Providence Alaska Medical Center - Anchorage
- Fairbanks Memorial Hospital - Fairbanks
Arizona
- Banner MD Anderson Cancer Center - Gilbert
- University of Arizona Cancer Center at Saint Joseph's - Phoenix
- University of Arizona Cancer Center-Orange Grove Campus - Tucson
- University of Arizona Cancer Center-North Campus - Tucson
- The University of Arizona Medical Center-University Campus - Tucson
- Yuma Cancer Center - Yuma
Arkansas
- CHI Saint Vincent Cancer Center Hot Springs - Hot Springs
- Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro - Jonesboro
- University of Arkansas for Medical Sciences - Little Rock
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,939 participants |
| Start Date | 2013-09-12 |
| Est. Completion | 2030-01 |
| Phase | Phase 3 |
What the registry record for NCT01674140 still lists
NCT01674140 is an interventional study that assigns participants to a tested intervention. Its 1,939 participants enrollment target places it among the larger protocols in the corpus, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (31% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which letrozole is the first listed.
NCT01674140 names 20 study sites across 4 states, led by Alaska, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT01674140 about?
NCT01674140 is a clinical study titled "S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer". RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate, goserelin acetate, leuprolide acetate, anastrozole, letrozole, or exemestane, may fight breast cancer by lowering the amount of estrogen the body makes. Everolimus may stop the growth of tumor c...
What is the current status of trial NCT01674140?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,939 participants. The study started on 2013-09-12. Estimated completion is 2030-01.
What conditions does trial NCT01674140 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT01674140?
The interventions under investigation include: letrozole (DRUG), everolimus (DRUG), anastrozole (DRUG), exemestane (DRUG), goserelin acetate (DRUG).
Who is sponsoring clinical trial NCT01674140?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01674140 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01674140's enrollment target sits among peer trials
1,939 70th of 1224 higher than 1,155 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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