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NCT01664741 · ClinicalTrials.gov registry record · Phase 4

Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging

A Phase 4 study of Nicotine Dependence, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 4
Development phase
127
Enrollment target
1
Study location

NCT01664741 is a Phase 4 study of Nicotine Dependence that has completed, run by Johns Hopkins University. The registered enrollment target is 127 participants, below the 185-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01664741, a Phase 4 study of Nicotine Dependence, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 4
Development phase
127 participants
Enrollment target
1
Study location

Study Summary

The proposed research will provide significant new gender-specific information of scientific and clinical relevance on the function of the mu-opioid system in nicotine dependence and therapeutic effectiveness of nicotine replacement therapy (NRT). The studies will help to explain the differences in the prevalence of smoking in men and women, sex-specific differences in nicotine craving and withdrawal as well as the poorer therapeutic response to NRT. This work may pave the way to the design of improved pharmacotherapies that can more effectively target the endogenous opioid system in the treatment of nicotine dependence.

Conditions Studied

Nicotine Dependence

Interventions

  • DRUG placebo
  • DRUG Nicotine patch - transdermal

Study Locations (1)

Maryland

  • Johns Hopkins University School of Medicine - Baltimore

Trial Details

FieldValue
Enrollment Target 127 participants
Start Date 2012-04
Est. Completion 2018-12
Phase Phase 4

Sponsor

Johns Hopkins University

1,448 total trials

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What the Registry Record Tells You About NCT01664741

The ClinicalTrials.gov registry entry for NCT01664741 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 127 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 185-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (31% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Nicotine Dependence appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT01664741 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT01664741 about?

NCT01664741 is a clinical study titled "Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging". The proposed research will provide significant new gender-specific information of scientific and clinical relevance on the function of the mu-opioid system in nicotine dependence and therapeutic effectiveness of nicotine replacement therapy (NRT). The studies will help to explain the differences in ...

What is the current status of trial NCT01664741?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 127 participants. The study started on 2012-04. Estimated completion is 2018-12.

What conditions does trial NCT01664741 study?

This clinical trial studies the following conditions: Nicotine Dependence.

What interventions are being tested in trial NCT01664741?

The interventions under investigation include: placebo (DRUG), Nicotine patch - transdermal (DRUG).

Who is sponsoring clinical trial NCT01664741?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01664741 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.