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NCT01649336 · ClinicalTrials.gov registry record · Phase 1

A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer

A Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

Completed
Registry status
Phase 1
Development phase
36
Enrollment target

NCT01649336 is a Phase 1 study that has completed, run by Array Biopharma, now a wholly owned subsidiary of Pfizer. The registered enrollment target is 36 participants.

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The verdict

NCT01649336, a Phase 1 study, has completed, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

This is a Phase 1 study during which patients with platinum-resistant epithelial ovarian, fallopian tube or primary peritoneal cancer will receive investigational study drug MEK162 and paclitaxel. Patients will receive increasing doses of study drug in combination with paclitaxel in order to achieve the highest dose of study drug possible that will not cause unacceptable side effects. Patients will be followed to see what side effects the combination causes and what effectiveness the combination has, if any, in treating the cancer. Approximately 36 patients from the US will be enrolled in this study.

Interventions

  • DRUG MEK162, MEK inhibitor; oral
  • DRUG Paclitaxel, mitotic inhibitor; intravenous

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2012-07
Est. Completion 2016-03
Phase Phase 1

What the Registry Record Tells You About NCT01649336

The ClinicalTrials.gov registry entry for NCT01649336 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which MEK162, MEK inhibitor; oral is the first listed.

NCT01649336 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01649336 about?

NCT01649336 is a clinical study titled "A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer". This is a Phase 1 study during which patients with platinum-resistant epithelial ovarian, fallopian tube or primary peritoneal cancer will receive investigational study drug MEK162 and paclitaxel. Patients will receive increasing doses of study drug in combination with paclitaxel in order to achieve...

What is the current status of trial NCT01649336?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2012-07. Estimated completion is 2016-03.

What interventions are being tested in trial NCT01649336?

The interventions under investigation include: MEK162, MEK inhibitor; oral (DRUG), Paclitaxel, mitotic inhibitor; intravenous (DRUG).

Who is sponsoring clinical trial NCT01649336?

This trial is sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.