Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01597167 · ClinicalTrials.gov registry record · NA

Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression

A NA study, sponsored by University of Miami.

Completed
Registry status
NA
Development phase
21
Enrollment target

NCT01597167: Completed NA study, sponsored by University of Miami.

NCT01597167 is a NA study that has completed, run by University of Miami. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01597167, a NA study, has completed, sponsored by University of Miami.

COMPLETED
Registry status
NA
Development phase
21 participants
Enrollment target

Study Summary

The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and females (21-70 years of age). Participants will be assessed at screening/baseline, day 1, day 2, day 7, and day 8. Each subject will be randomized in a double-blind fashion to receive either IV infusion of magnesium sulfate or 5% dextrose followed by a washout period of 5 days then crossover to receive either IV infusion of 5% dextrose or magnesium sulfate.

Primary Outcome

To investigate the magnesium deficient status in treatment-resistant mild and moderate depression patients via assay of 24-hour urine magnesium, blood magnesium, and EXATEST of intracellular magnesium of epithelial cells before and after IV infusion.

Interventions

  • DIETARY_SUPPLEMENT Magnesium sulfate

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2011-10
Est. Completion 2014-12
Phase NA
University of Miami

721 total trials

What the finished NCT01597167 record still lists

NCT01597167 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Magnesium sulfate is the first listed.

NCT01597167 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01597167 about?

NCT01597167 is a clinical study titled "Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression". The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and females (21-70 years of age). Participants will be assessed at screening...

What is the current status of trial NCT01597167?

This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2011-10. Estimated completion is 2014-12.

What interventions are being tested in trial NCT01597167?

The interventions under investigation include: Magnesium sulfate (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01597167?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01597167's enrollment target sits among peer trials

21 1762nd of 2000 higher than 233 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02447874 · 21 participants · Phase 1

    Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

  • NCT03826992 · 21 participants · Phase 1

    Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

  • NCT04107077 · 21 participants · Phase 2

    Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

  • NCT04158635 · 21 participants · Phase 1

    Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01597167, the US trial registry maintained by the National Library of Medicine. NCT01597167 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.