Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01589692 · ClinicalTrials.gov registry record · NA
A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 304
- Enrollment target
NCT01589692: Completed NA study, sponsored by University of Michigan.
NCT01589692 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 304 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01589692, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 304 participants
- Enrollment target
Study Summary
In the United States, over 300,000 individuals over age 65 suffer from distal radius fractures (DRFs) each year. Despite the frequency of this injury and over 200 years of experience treating DRFs, management of elderly DRFs is still controversial. Close reduction and casting is a nonsurgical technique that is frequently used, but osteoporotic fractures, common in the elderly, often collapse and displace. The three currently applied surgical techniques are close reduction and percutaneous pinning, external fixation with or without percutaneous pinning, and internal fixation with volar locking plating. Preliminary evidence indicates that locking plate fixation can permit elderly patients to move their hands and wrists much sooner in order to return to self-care activities more quickly. Although these outcomes are promising, there is no randomized controlled clinical trial to demonstrate that the more invasive, and perhaps more costly, plating technique is superior to the other simpler approaches. The specific aim of this 24-center randomized controlled trial is to compare outcomes of these three surgical techniques in treating unstable DRFs in the elderly. The secondary aim is to follow a cohort of elderly patients who choose not to have surgery to evaluate outcomes following treatment by close reduction and casting alone. This clinical trial is the most ambitious study in hand surgery by assembling most of the leading centers in North America to collect evidence-based data to guide future treatment of this prevalent injury in the growing elderly population.
Primary Outcome
upper-extremity questionnaire
Interventions
- PROCEDURE Open Reduction and Internal Fixation
- PROCEDURE External Fixation
- PROCEDURE Percutaneous Pinning
- PROCEDURE Closed Reduction and casting
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 304 participants |
| Start Date | 2012-04-10 |
| Est. Completion | 2019-01-08 |
| Phase | NA |
What the finished NCT01589692 record still lists
NCT01589692 is an interventional study that assigns participants to a tested intervention. The registered 304 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 4 interventions - of which Open Reduction and Internal Fixation is the first listed.
NCT01589692 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01589692 about?
NCT01589692 is a clinical study titled "A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures". In the United States, over 300,000 individuals over age 65 suffer from distal radius fractures (DRFs) each year. Despite the frequency of this injury and over 200 years of experience treating DRFs, management of elderly DRFs is still controversial. Close reduction and casting is a nonsurgical techni...
What is the current status of trial NCT01589692?
This trial is currently completed. It is a NA study. The enrollment target is 304 participants. The study started on 2012-04-10. Estimated completion is 2019-01-08.
What interventions are being tested in trial NCT01589692?
The interventions under investigation include: Open Reduction and Internal Fixation (PROCEDURE), External Fixation (PROCEDURE), Percutaneous Pinning (PROCEDURE), Closed Reduction and casting (PROCEDURE).
Who is sponsoring clinical trial NCT01589692?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01589692's enrollment target sits among peer trials
304 327th of 2000 higher than 1,672 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04750616 · 304 participants · Phase 2
NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial
- NCT04994717 · 304 participants · Phase 3
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
- NCT06036147 · 304 participants · NA
Concussion Health Improvement Program
- NCT06096844 · 304 participants · Phase 3
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI