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NCT01512589 · ClinicalTrials.gov registry record · Phase 2
Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial
A Phase 2 study of Esophageal Cancer, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 147
- Enrollment target
- 1
- Study location
NCT01512589: Active Phase 2 study of Esophageal Cancer, sponsored by M.D. Anderson Cancer Center.
NCT01512589 is a Phase 2 study of Esophageal Cancer that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 147 participants, below the 498-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01512589, a Phase 2 study of Esophageal Cancer, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 147 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical research study is to learn how safe and effective proton-beam therapy (PBT) may be in comparison to intensity modulated radiation therapy (IMRT) in combination with chemotherapy in patients with esophageal cancer. PBT and IMRT are both forms of radiation therapy that are designed to treat a specific area of the body while affecting as little of the surrounding normal tissue as possible. PBT is a newer technology that is designed to further reduce the amount of radiation that affects the surrounding normal tissue. However, this is still being studied.
Primary Outcome
Defined from the time of enrollment to the date of death or any recurrence. The progression-free survival (PFS) time distribution will be estimated in each treatment arm using the Kaplan-Meier method.
Conditions Studied
Interventions
- RADIATION Intensity Modulated Radiation Therapy (IMRT)
- BEHAVIORAL Questionnaires
- RADIATION Proton Beam Therapy (PBT)
Study Locations (1)
Texas
- MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 147 participants |
| Start Date | 2012-04-30 |
| Est. Completion | 2027-04-30 |
| Phase | Phase 2 |
What the registry record for NCT01512589 still lists
NCT01512589 is an interventional study that assigns participants to a tested intervention. The registered 147 participants enrollment target is mid-sized for trials with a published cap, below the 498-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (70% lower).
The record links to 1 condition, with Esophageal Cancer appearing as the primary indexed condition, and to 3 interventions - of which Intensity Modulated Radiation Therapy (IMRT) is the first listed.
NCT01512589 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01512589 about?
NCT01512589 is a clinical study titled "Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial". The goal of this clinical research study is to learn how safe and effective proton-beam therapy (PBT) may be in comparison to intensity modulated radiation therapy (IMRT) in combination with chemotherapy in patients with esophageal cancer. PBT and IMRT are both forms of radiation therapy that are d...
What is the current status of trial NCT01512589?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 147 participants. The study started on 2012-04-30. Estimated completion is 2027-04-30.
What conditions does trial NCT01512589 study?
This clinical trial studies the following conditions: Esophageal Cancer.
What interventions are being tested in trial NCT01512589?
The interventions under investigation include: Intensity Modulated Radiation Therapy (IMRT) (RADIATION), Questionnaires (BEHAVIORAL), Proton Beam Therapy (PBT) (RADIATION).
Who is sponsoring clinical trial NCT01512589?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01512589 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Esophageal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01512589's enrollment target sits among peer trials
147 42nd of 123 higher than 82 of 123 other Esophageal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Esophageal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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