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NCT01497483 · ClinicalTrials.gov registry record · Phase 1
Drug-Drug Interaction Study With Pravastatin and Cyclosporine
A Phase 1 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
NCT01497483 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 21 participants.
The verdict
NCT01497483, a Phase 1 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
Study Summary
This study will address the following question: Does cyclosporine affect the pharmacokinetics of pravastatin in healthy volunteers? Studies have shown that cyclosporine inhibits the organic anion transporter required for pravastatin transport into the liver, thus increasing pravastatin levels in the blood. The investigators hypothesize that this inhibition will vary among people based on genetic differences. This knowledge is important to help develop safer and more effective drug therapy with reduced side effects.
Interventions
- DRUG Pravastatin alone
- DRUG Pravastatin and Cyclosporine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2011-12 |
| Est. Completion | 2013-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01497483
The ClinicalTrials.gov registry entry for NCT01497483 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Pravastatin alone is the first listed.
NCT01497483 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01497483 about?
NCT01497483 is a clinical study titled "Drug-Drug Interaction Study With Pravastatin and Cyclosporine". This study will address the following question: Does cyclosporine affect the pharmacokinetics of pravastatin in healthy volunteers? Studies have shown that cyclosporine inhibits the organic anion transporter required for pravastatin transport into the liver, thus increasing pravastatin levels in the...
What is the current status of trial NCT01497483?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2011-12. Estimated completion is 2013-12.
What interventions are being tested in trial NCT01497483?
The interventions under investigation include: Pravastatin alone (DRUG), Pravastatin and Cyclosporine (DRUG).
Who is sponsoring clinical trial NCT01497483?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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