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NCT01492933 · ClinicalTrials.gov registry record
Measuring Effects of Alcohol on Brain Chemistry
A clinical trial, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- Terminated
- Registry status
- 34
- Enrollment target
NCT01492933 is a clinical trial that was terminated before completion, run by National Institute on Alcohol Abuse and Alcoholism (NIAAA). The registered enrollment target is 34 participants.
The verdict
NCT01492933 was terminated before completion, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- TERMINATED
- Registry status
- 34 participants
- Enrollment target
Study Summary
Background: \- Studies show that alcohol changes the amount of many brain chemicals. These changes may be related to continued drinking, craving for alcohol, and relapse. This study will use magnetic resonance imaging (MRI) to look at brain areas and brain chemistry during an infusion of alcohol. It will also study how changes in brain chemistry relate to participant reports of feeling drunk. Objectives: \- To use magnetic resonance imaging to measure the effect of alcohol on brain chemistry Eligibility: * Individuals between 21 and 45 years of age. * Participants will be either light drinkers (1 to 14 standard alcoholic drinks per week) or heavy drinkers (20 to 40 standard alcoholic drinks per week). A standard drink is a 12-ounce beer, a 4-ounce glass of wine, or a shot of liquor. * Participants must be able to go without alcohol for at least 3 days in a row without severe withdrawal symptoms. Design: * This study requires two or three outpatient visits to the NIH Clinical Center. * Participants will have a physical exam and medical history. Blood and urine samples will be collected. Participants' alcohol drinking habits will also be assessed to determine whether they may have an alcohol use disorder. * At the first study visit, participants will have an infusion of alcohol. Blood samples will be collected to measure blood alcohol levels. * The MRI study visit will take place about 3 days after the first study visit. Participants will have an MRI scan of the brain, followed by an infusion of alcohol and another scan. Blood samples will be collected. * Participants will complete questionnaires before and after each infusion to measure their response to alcohol. * Heavy drinkers will come to the clinic for a third visit to discuss possible future treatment and any risky behavior associated with their high levels of alcohol use.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2011-11-22 |
| Est. Completion | 2015-02-24 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01492933
The ClinicalTrials.gov registry entry for NCT01492933 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01492933 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01492933 about?
NCT01492933 is a clinical study titled "Measuring Effects of Alcohol on Brain Chemistry". Background: \- Studies show that alcohol changes the amount of many brain chemicals. These changes may be related to continued drinking, craving for alcohol, and relapse. This study will use magnetic resonance imaging (MRI) to look at brain areas and brain chemistry during an infusion of alcohol. I...
What is the current status of trial NCT01492933?
This trial is currently terminated. The enrollment target is 34 participants. The study started on 2011-11-22. Estimated completion is 2015-02-24.
Who is sponsoring clinical trial NCT01492933?
This trial is sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total clinical trials registered on ClinicalTrials.gov.
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