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NCT01488318 · ClinicalTrials.gov registry record · Phase 2

Cetuximab and Dasatinib in Recurrent Squamous Cell Carcinoma

A Phase 2 study, sponsored by Julie E. Bauman, MD, MPH.

Terminated
Registry status
Phase 2
Development phase
21
Enrollment target

NCT01488318: Clinical Trial Phase 2 study, sponsored by Julie E. Bauman, MD, MPH.

NCT01488318 is a Phase 2 study that was terminated before completion, run by Julie E. Bauman, MD, MPH. The registered enrollment target is 21 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01488318, a Phase 2 study, was terminated before completion, sponsored by Julie E. Bauman, MD, MPH.

TERMINATED
Registry status
Phase 2
Development phase
21 participants
Enrollment target

Study Summary

This is a single-arm, non-masked, open-label, Phase II study of cetuximab + dasatinib in recurrent Squamous Cell Carcinoma of The Head and Neck (SCCHN) that has recurred after cetuximab-containing therapy (please see attached schema). The primary endpoint 12-week PFS.

Primary Outcome

Number of patients experiencing a Complete Response (CR) + Partial Response (PR) to study treatment / Total number of evaluable patients, per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1.

Interventions

  • DRUG Cetuximab
  • DRUG Dasatinib

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2011-09
Est. Completion 2016-08
Phase Phase 2
Julie E. Bauman, MD, MPH

4 total trials

Why NCT01488318 stopped before completion

NCT01488318 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% lower).

The record links to 0 conditions, and to 2 interventions - of which Cetuximab is the first listed.

NCT01488318 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01488318 about?

NCT01488318 is a clinical study titled "Cetuximab and Dasatinib in Recurrent Squamous Cell Carcinoma". This is a single-arm, non-masked, open-label, Phase II study of cetuximab + dasatinib in recurrent Squamous Cell Carcinoma of The Head and Neck (SCCHN) that has recurred after cetuximab-containing therapy (please see attached schema). The primary endpoint 12-week PFS.

What is the current status of trial NCT01488318?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2011-09. Estimated completion is 2016-08.

What interventions are being tested in trial NCT01488318?

The interventions under investigation include: Cetuximab (DRUG), Dasatinib (DRUG).

Who is sponsoring clinical trial NCT01488318?

This trial is sponsored by Julie E. Bauman, MD, MPH, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01488318's enrollment target sits among peer trials

21 1794th of 2000 higher than 196 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01488318, the US trial registry maintained by the National Library of Medicine. NCT01488318 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.