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NCT01477034 · ClinicalTrials.gov registry record · NA
Vitamin D and Adipose Tissue Inflammation
A NA study of Obesity and Type 2 Diabetes Mellitus, sponsored by Fred Hutchinson Cancer Center.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT01477034: Completed NA study of Obesity and Type 2 Diabetes Mellitus, sponsored by Fred Hutchinson Cancer Center.
NCT01477034 is a NA study of Obesity and Type 2 Diabetes Mellitus that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 18 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01477034, a NA study of Obesity and Type 2 Diabetes Mellitus, has completed, sponsored by Fred Hutchinson Cancer Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic, low-grade adipose tissue inflammation is a major risk factor for type 2 diabetes mellitus. The cause of adipose tissue inflammation has remained largely unclear. We hypothesize that vitamin D deficiency predisposes individuals to the development of adipose tissue inflammation, and that treatment of vitamin D deficient subjects with high dose vitamin D will reduce adipose tissue inflammation.
Primary Outcome
Total RNA will be extracted from whole adipose tissue. TNF alpha mRNA will be quantified using PCR, and normalized using a normalization factor based on three housekeeping genes. We will compute the change in adipose tissue TNF alpha mRNA level between baseline and the 6 month visit.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Vitamin D3
Study Locations (1)
Washington
- Fred Hutchinson Cancer Research Center - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2011-11 |
| Est. Completion | 2013-06 |
| Phase | NA |
What the finished NCT01477034 record still lists
NCT01477034 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower).
The record links to 4 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Vitamin D3 is the first listed.
NCT01477034 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT01477034 about?
NCT01477034 is a clinical study titled "Vitamin D and Adipose Tissue Inflammation". Chronic, low-grade adipose tissue inflammation is a major risk factor for type 2 diabetes mellitus. The cause of adipose tissue inflammation has remained largely unclear. We hypothesize that vitamin D deficiency predisposes individuals to the development of adipose tissue inflammation, and that trea...
What is the current status of trial NCT01477034?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2011-11. Estimated completion is 2013-06.
What conditions does trial NCT01477034 study?
This clinical trial studies the following conditions: Obesity, Type 2 Diabetes Mellitus, Vitamin D Deficiency, Intestinal Permeability.
What interventions are being tested in trial NCT01477034?
The interventions under investigation include: Vitamin D3 (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01477034?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01477034 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01477034's enrollment target sits among peer trials
18 982nd of 1053 higher than 64 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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