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NCT01462630 · ClinicalTrials.gov registry record · Phase 2

Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma

A Phase 2 study, sponsored by Fox Chase Cancer Center.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT01462630: Completed Phase 2 study, sponsored by Fox Chase Cancer Center.

NCT01462630 is a Phase 2 study that has completed, run by Fox Chase Cancer Center. The registered enrollment target is 29 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01462630, a Phase 2 study, has completed, sponsored by Fox Chase Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

This phase II trial studies how well pazopanib hydrochloride works in treating patients with advanced angiosarcoma. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Primary Outcome

Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1), as a 20% increase in the sum of the longest diameter of target lesions, or a measurable increase in a non-target lesion, or the appearance of new lesions. PFS was estimated using the method of Kaplan and Meier.

Interventions

  • OTHER laboratory biomarker analysis
  • RADIATION fludeoxyglucose F 18
  • PROCEDURE positron emission tomography
  • PROCEDURE computed tomography
  • DRUG pazopanib hydrochloride

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2011-11-03
Est. Completion 2021-01-12
Phase Phase 2
Fox Chase Cancer Center

183 total trials

What the finished NCT01462630 record still lists

NCT01462630 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower).

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT01462630 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01462630 about?

NCT01462630 is a clinical study titled "Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma". This phase II trial studies how well pazopanib hydrochloride works in treating patients with advanced angiosarcoma. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

What is the current status of trial NCT01462630?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2011-11-03. Estimated completion is 2021-01-12.

What interventions are being tested in trial NCT01462630?

The interventions under investigation include: laboratory biomarker analysis (OTHER), fludeoxyglucose F 18 (RADIATION), positron emission tomography (PROCEDURE), computed tomography (PROCEDURE), pazopanib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT01462630?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01462630's enrollment target sits among peer trials

29 1669th of 2000 higher than 324 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01462630, the US trial registry maintained by the National Library of Medicine. NCT01462630 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.