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NCT01446003 · ClinicalTrials.gov registry record · Phase 1
A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 31
- Enrollment target
NCT01446003 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 31 participants.
The verdict
NCT01446003, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 31 participants
- Enrollment target
Study Summary
This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic blood pressure in participants with mild to moderate hypertension in addition to safety and tolerability. The study hypothesis is that MK-8457 does not increase systolic blood pressure to a clinically significant extent, as measured by 24-hour mean ambulatory systolic blood pressure change from baseline after 10 days of dosing.
Interventions
- DRUG MK-8457
- DRUG Placebo for MK-8457
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2011-10-25 |
| Est. Completion | 2012-03-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01446003
The ClinicalTrials.gov registry entry for NCT01446003 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which MK-8457 is the first listed.
NCT01446003 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01446003 about?
NCT01446003 is a clinical study titled "A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)". This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic blood pressure in participants with mild to moderate hypertension in addition to safety and tolerability. The study hypothesis is that MK-8457 does not increase systolic blood pressure to a clinically signifi...
What is the current status of trial NCT01446003?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2011-10-25. Estimated completion is 2012-03-03.
What interventions are being tested in trial NCT01446003?
The interventions under investigation include: MK-8457 (DRUG), Placebo for MK-8457 (DRUG).
Who is sponsoring clinical trial NCT01446003?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
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