Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01429285 · ClinicalTrials.gov registry record · Phase 4

Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain

A Phase 4 study of Pain, sponsored by Montefiore Medical Center.

Completed
Registry status
Phase 4
Development phase
350
Enrollment target
1
Study location

NCT01429285: Completed Phase 4 study of Pain, sponsored by Montefiore Medical Center.

NCT01429285 is a Phase 4 study of Pain that has completed, run by Montefiore Medical Center. The registered enrollment target is 350 participants, above the 303-participant average among 374 other Pain trials with a reported enrollment target (16% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01429285, a Phase 4 study of Pain, has completed, sponsored by Montefiore Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
350 participants
Enrollment target
1
Study location

Study Summary

The hydromorphone protocol is more effective than usual care in Emergency Department (ED) patients age 65 years and older in terms of proportion who choose to forgo additional pain medication within 60 minutes post-baseline in the two groups.

Primary Outcome

Number of patients with "successful treatment" is defined as the number of patients who declined additional pain medication within 1 hour of study entry when asked the question, "Do you want more pain medication?". This measure looks at declining pain medication at either 15 minutes or 60 minutes, whereas 4. Post-Hoc refers only to the answer to the question at the 60 minute mark post-baseline.

Conditions Studied

Interventions

  • DRUG Hydromorphone
  • DRUG Usual care

Study Locations (1)

New York

  • Montefiore Emergency Department - The Bronx

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2009-07
Est. Completion 2012-06
Phase Phase 4
Montefiore Medical Center

345 total trials

What the finished NCT01429285 record still lists

NCT01429285 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, above the 303-participant average among 374 other Pain trials with a reported enrollment target (16% higher).

The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Hydromorphone is the first listed.

NCT01429285 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT01429285 about?

NCT01429285 is a clinical study titled "Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain". The hydromorphone protocol is more effective than usual care in Emergency Department (ED) patients age 65 years and older in terms of proportion who choose to forgo additional pain medication within 60 minutes post-baseline in the two groups.

What is the current status of trial NCT01429285?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 350 participants. The study started on 2009-07. Estimated completion is 2012-06.

What conditions does trial NCT01429285 study?

This clinical trial studies the following conditions: Pain.

What interventions are being tested in trial NCT01429285?

The interventions under investigation include: Hydromorphone (DRUG), Usual care (DRUG).

Who is sponsoring clinical trial NCT01429285?

This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01429285 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01429285's enrollment target sits among peer trials

350 52nd of 374 higher than 322 of 374 other Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00900575 · 350 participants · NA

    Cervical Cancer Detection Using Optical Spectroscopy

  • NCT01627821 · 350 participants · NA

    Evaluation of the Jarvik 2000 Left Ventricular Assist System With Post-Auricular Connector--Destination Therapy Study

  • NCT02357654 · 350 participants · Phase 4

    GnRH for Luteal Support in IVF/ICSI/FET Cycles

  • NCT03997370 · 350 participants · Phase 1

    Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01429285, the US trial registry maintained by the National Library of Medicine. NCT01429285 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.