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NCT01370460 · ClinicalTrials.gov registry record · Phase 2
Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty
A Phase 2 study of Osteoarthritis, Knee and Acute Blood Loss Anemia, sponsored by Henry Ford Health System.
- Completed
- Registry status
- Phase 2
- Development phase
- 101
- Enrollment target
- 1
- Study location
NCT01370460: Completed Phase 2 study of Osteoarthritis, Knee and Acute Blood Loss Anemia, sponsored by Henry Ford Health System.
NCT01370460 is a Phase 2 study of Osteoarthritis, Knee and Acute Blood Loss Anemia that has completed, run by Henry Ford Health System. The registered enrollment target is 101 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01370460, a Phase 2 study of Osteoarthritis, Knee and Acute Blood Loss Anemia, has completed, sponsored by Henry Ford Health System.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 101 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to assess postoperative blood loss and transfusion rates in total knee replacement after one-time administration of topical tranexamic acid.
Primary Outcome
Preoperative and lowest postoperative hemoglobin. Blood loss was calculated taking change in hemoglobin as described (units g/dL) and converting to blood loss (mL) according to the formulas included in the papers cited in this entry (Good 2003 Br J Anesthesia; Nadler 1962 Surgery, http://www.ncbi.nlm.nih.gov/pubmed/21936146).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Tranexamic Acid
Study Locations (1)
Michigan
- Henry Ford Hospital - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2011-06 |
| Est. Completion | 2012-09 |
| Phase | Phase 2 |
What the finished NCT01370460 record still lists
NCT01370460 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (80% lower).
The record links to 2 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01370460 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT01370460 about?
NCT01370460 is a clinical study titled "Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty". This study aims to assess postoperative blood loss and transfusion rates in total knee replacement after one-time administration of topical tranexamic acid.
What is the current status of trial NCT01370460?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 101 participants. The study started on 2011-06. Estimated completion is 2012-09.
What conditions does trial NCT01370460 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Acute Blood Loss Anemia.
What interventions are being tested in trial NCT01370460?
The interventions under investigation include: Placebo (DRUG), Tranexamic Acid (DRUG).
Who is sponsoring clinical trial NCT01370460?
This trial is sponsored by Henry Ford Health System, which has 234 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01370460 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01370460's enrollment target sits among peer trials
101 64th of 112 higher than 49 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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