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NCT01355796 · ClinicalTrials.gov registry record · Phase 1
Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis
A Phase 1 study of Cystic Fibrosis, sponsored by Joseph Zabner.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 2
- Study locations
NCT01355796 is a Phase 1 study of Cystic Fibrosis that has completed, run by Joseph Zabner. The registered enrollment target is 30 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (83% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT01355796, a Phase 1 study of Cystic Fibrosis, has completed, sponsored by Joseph Zabner.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 2
- Study locations
Study Summary
Cystic fibrosis (CF) lung disease is characterized by chronic bacterial colonization and recurrent infection of the airways. Lowering the airway surface liquid (ASL) salt concentration has been shown to increase activity of salt sensitive antimicrobial peptides. Xylitol is a 5-carbon sugar that can lower the ASL salt concentration, thus enhancing innate immunity.In this study, the investigators plan to study the safety and efficacy of 2 weeks of inhaled xylitol compared to 2 weeks of hypertonic saline in a randomized crossover design in stable subjects with cystic fibrosis
Conditions Studied
Interventions
- DRUG Hypertonic saline
- DRUG Xylitol
Study Locations (2)
Illinois
- Northwestern University - Chicago
- Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2011-05 |
| Est. Completion | 2015-02 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01355796
The ClinicalTrials.gov registry entry for NCT01355796 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (83% lower). The listed sponsor is Joseph Zabner, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 2 interventions - of which Hypertonic saline is the first listed.
NCT01355796 reports 2 study locations spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT01355796 about?
NCT01355796 is a clinical study titled "Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis". Cystic fibrosis (CF) lung disease is characterized by chronic bacterial colonization and recurrent infection of the airways. Lowering the airway surface liquid (ASL) salt concentration has been shown to increase activity of salt sensitive antimicrobial peptides. Xylitol is a 5-carbon sugar that can...
What is the current status of trial NCT01355796?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2011-05. Estimated completion is 2015-02.
What conditions does trial NCT01355796 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT01355796?
The interventions under investigation include: Hypertonic saline (DRUG), Xylitol (DRUG).
Who is sponsoring clinical trial NCT01355796?
This trial is sponsored by Joseph Zabner, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01355796 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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