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NCT07283770 · ClinicalTrials.gov registry record · Phase 1
Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants
A Phase 1 study of Cystic Fibrosis, sponsored by Vertex Pharmaceuticals Incorporated.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 128
- Enrollment target
- 1
- Study location
NCT07283770 is a Phase 1 study of Cystic Fibrosis that is actively recruiting participants, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 128 participants, below the 178-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (28% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07283770, a Phase 1 study of Cystic Fibrosis, is actively recruiting participants, sponsored by Vertex Pharmaceuticals Incorporated.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 128 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending doses of VX-581.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG VX-581
Study Locations (1)
Kansas
- Altasciences - Kansas City - Overland Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2025-12-09 |
| Est. Completion | 2026-11-19 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07283770
The ClinicalTrials.gov registry entry for NCT07283770 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 178-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (28% lower). The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07283770 reports 1 study location spanning 1 distinct geographic area - top geographies include Kansas.
Frequently Asked Questions
What is clinical trial NCT07283770 about?
NCT07283770 is a clinical study titled "Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants". The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending doses of VX-581.
What is the current status of trial NCT07283770?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 128 participants. The study started on 2025-12-09. Estimated completion is 2026-11-19.
What conditions does trial NCT07283770 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT07283770?
The interventions under investigation include: Placebo (DRUG), VX-581 (DRUG).
Who is sponsoring clinical trial NCT07283770?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07283770 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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