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NCT01301443 · ClinicalTrials.gov registry record · Phase 1
Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)
A Phase 1 study, sponsored by Oxford BioMedica.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
NCT01301443: Completed Phase 1 study, sponsored by Oxford BioMedica.
NCT01301443 is a Phase 1 study that has completed, run by Oxford BioMedica. The registered enrollment target is 21 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01301443, a Phase 1 study, has completed, sponsored by Oxford BioMedica.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
Study Summary
The purpose of this first in man study is to examine the safety of an experimental gene transfer agent, RetinoStat, designed to treat neovascular age-related macular degeneration.
Primary Outcome
The number and percentage of patients with treatment emergent adverse events.
Interventions
- DRUG Subretinally injected RetinoStat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2011-02 |
| Est. Completion | 2015-05 |
| Phase | Phase 1 |
What the finished NCT01301443 record still lists
NCT01301443 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower).
The record links to 0 conditions, and to 1 intervention - of which Subretinally injected RetinoStat is the first listed.
NCT01301443 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01301443 about?
NCT01301443 is a clinical study titled "Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)". The purpose of this first in man study is to examine the safety of an experimental gene transfer agent, RetinoStat, designed to treat neovascular age-related macular degeneration.
What is the current status of trial NCT01301443?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2011-02. Estimated completion is 2015-05.
What interventions are being tested in trial NCT01301443?
The interventions under investigation include: Subretinally injected RetinoStat (DRUG).
Who is sponsoring clinical trial NCT01301443?
This trial is sponsored by Oxford BioMedica, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01301443's enrollment target sits among peer trials
21 1615th of 2000 higher than 372 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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