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NCT01281592 · ClinicalTrials.gov registry record · Phase 1
A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours
A Phase 1 study, sponsored by Aptose Biosciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT01281592: Completed Phase 1 study, sponsored by Aptose Biosciences.
NCT01281592 is a Phase 1 study that has completed, run by Aptose Biosciences. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01281592, a Phase 1 study, has completed, sponsored by Aptose Biosciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
This is an open-label, phase 1 study to determine the maximum tolerated dose (MTD) or appropriate target dose if MTD not reached to identify the recommended phase 2 dose of LOR-253 HCl in patients with advanced or metastatic solid tumours.
Interventions
- DRUG LOR-253 HCl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2011-01 |
| Est. Completion | 2014-01 |
| Phase | Phase 1 |
What the finished NCT01281592 record still lists
NCT01281592 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 1 intervention - of which LOR-253 HCl is the first listed.
NCT01281592 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01281592 about?
NCT01281592 is a clinical study titled "A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours". This is an open-label, phase 1 study to determine the maximum tolerated dose (MTD) or appropriate target dose if MTD not reached to identify the recommended phase 2 dose of LOR-253 HCl in patients with advanced or metastatic solid tumours.
What is the current status of trial NCT01281592?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2011-01. Estimated completion is 2014-01.
What interventions are being tested in trial NCT01281592?
The interventions under investigation include: LOR-253 HCl (DRUG).
Who is sponsoring clinical trial NCT01281592?
This trial is sponsored by Aptose Biosciences, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01281592's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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