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NCT01274624 · ClinicalTrials.gov registry record · Phase 1
Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer
A Phase 1 study, sponsored by Oncolytics Biotech.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT01274624: Completed Phase 1 study, sponsored by Oncolytics Biotech.
NCT01274624 is a Phase 1 study that has completed, run by Oncolytics Biotech. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01274624, a Phase 1 study, has completed, sponsored by Oncolytics Biotech.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
This is a Phase 1 dose-escalation study with three dose levels to determine the maximum tolerated dose of REOLYSIN® combined with FOLFIRI and bevacizumab.
Interventions
- DRUG Bevacizumab
- DRUG Leucovorin
- DRUG Irinotecan
- DRUG Fluorouracil (5-FU)
- BIOLOGICAL REOLYSIN®
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2010-12 |
| Est. Completion | 2018-11 |
| Phase | Phase 1 |
What the finished NCT01274624 record still lists
NCT01274624 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 5 interventions - of which Bevacizumab is the first listed.
NCT01274624 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01274624 about?
NCT01274624 is a clinical study titled "Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer". This is a Phase 1 dose-escalation study with three dose levels to determine the maximum tolerated dose of REOLYSIN® combined with FOLFIRI and bevacizumab.
What is the current status of trial NCT01274624?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2010-12. Estimated completion is 2018-11.
What interventions are being tested in trial NCT01274624?
The interventions under investigation include: Bevacizumab (DRUG), Leucovorin (DRUG), Irinotecan (DRUG), Fluorouracil (5-FU) (DRUG), REOLYSIN® (BIOLOGICAL).
Who is sponsoring clinical trial NCT01274624?
This trial is sponsored by Oncolytics Biotech, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01274624's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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