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NCT01240265 · ClinicalTrials.gov registry record · Phase 2

Vitamin D Supplementation in Breastfeeding Women

A Phase 2 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 2
Development phase
80
Enrollment target

NCT01240265: Completed Phase 2 study, sponsored by Mayo Clinic.

NCT01240265 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 80 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01240265, a Phase 2 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 2
Development phase
80 participants
Enrollment target

Study Summary

Adequate vitamin D is essential for proper infant growth and development. However, human milk is low in vitamin D, and most infants do not receive recommended supplementation. Our aim is to assess the feasibility of providing adequate vitamin D to breastfed infants through maternal vitamin D supplementation. Forty non-pregnant, lactating women at least 18 years of age with exclusively breastfed infants between the ages of 1 and 6 months will be randomized to receive oral vitamin D as either 5,000 IU daily for 28 days or 150,000 IU as a single dose. Maternal serum calcium, phosphorus, vitamin D and 25(OH)D; maternal urinary calcium; maternal milk vitamin D and 25(OH)D will be measured on days 0, 1, 3, 7, 14, and 28 of the study; and infant serum vitamin D and 25(OH)D will be measured on days 0 and 28.

Primary Outcome

To compare the number of days of detectable milk vitamin D concentrations and incremental area under the curve between two dosing regimens of oral cholecalciferol in lactating mothers.

Interventions

  • DIETARY_SUPPLEMENT Vitamin D3

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2010-12
Est. Completion 2011-08
Phase Phase 2
Mayo Clinic

2,844 total trials

What the finished NCT01240265 record still lists

NCT01240265 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 1 intervention - of which Vitamin D3 is the first listed.

NCT01240265 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01240265 about?

NCT01240265 is a clinical study titled "Vitamin D Supplementation in Breastfeeding Women". Adequate vitamin D is essential for proper infant growth and development. However, human milk is low in vitamin D, and most infants do not receive recommended supplementation. Our aim is to assess the feasibility of providing adequate vitamin D to breastfed infants through maternal vitamin D supplem...

What is the current status of trial NCT01240265?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2010-12. Estimated completion is 2011-08.

What interventions are being tested in trial NCT01240265?

The interventions under investigation include: Vitamin D3 (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01240265?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01240265's enrollment target sits among peer trials

80 842nd of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01240265, the US trial registry maintained by the National Library of Medicine. NCT01240265 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.