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NCT01238445 · ClinicalTrials.gov registry record

Assessing Response to Albuterol in Bronchiolitis

A clinical trial of Bronchiolitis, sponsored by Connecticut Children's Medical Center.

Completed
Registry status
29
Enrollment target
1
Study location

NCT01238445 is a study of Bronchiolitis that has completed, run by Connecticut Children's Medical Center. The registered enrollment target is 29 participants, below the 574-participant average among 12 other Bronchiolitis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01238445, a study of Bronchiolitis, has completed, sponsored by Connecticut Children's Medical Center.

COMPLETED
Registry status
29 participants
Enrollment target
1
Study location

Study Summary

Bronchiolitis is a significant cause of morbidity and hospitalizations in children, accounting for more than 125,000 hospitalized children per year in the United States. Although treatment is largely supportive, bronchodilator medications such as albuterol are frequently used due to increased pulmonary resistance in this population.2-4 However, despite four decades of clinical trials, the efficacy of albuterol in the treatment of bronchiolitis has yet to be proven. This inconsistency is due in part to the lack of sufficiently sensitive methods for the evaluation of lung function and thus the response to albuterol in infants. Because of the difficulties in evaluating the response to therapy, healthcare providers are forced to rely on their physical examination skills or a clinical scoring system, both of which are highly subjective in this population. The investigators propose to conduct a prospective observational study of healthcare providers to determine the accuracy of clinical assessment as compared to that of pulmonary mechanics in a population of children intubated and mechanically ventilated for bronchiolitis.

Conditions Studied

Study Locations (1)

Connecticut

  • Connecticut Children's Medical Center - Hartford

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2010-11
Est. Completion 2016-11

What the Registry Record Tells You About NCT01238445

The ClinicalTrials.gov registry entry for NCT01238445 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 574-participant average among 12 other Bronchiolitis trials with a reported enrollment target (95% lower). The listed sponsor is Connecticut Children's Medical Center, which has 55 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Bronchiolitis appearing as the primary indexed condition, and to 0 interventions.

NCT01238445 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT01238445 about?

NCT01238445 is a clinical study titled "Assessing Response to Albuterol in Bronchiolitis". Bronchiolitis is a significant cause of morbidity and hospitalizations in children, accounting for more than 125,000 hospitalized children per year in the United States. Although treatment is largely supportive, bronchodilator medications such as albuterol are frequently used due to increased pulmon...

What is the current status of trial NCT01238445?

This trial is currently completed. The enrollment target is 29 participants. The study started on 2010-11. Estimated completion is 2016-11.

What conditions does trial NCT01238445 study?

This clinical trial studies the following conditions: Bronchiolitis.

Who is sponsoring clinical trial NCT01238445?

This trial is sponsored by Connecticut Children's Medical Center, which has 55 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01238445 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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