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NCT01238445 · ClinicalTrials.gov registry record
Assessing Response to Albuterol in Bronchiolitis
A clinical trial of Bronchiolitis, sponsored by Connecticut Children's Medical Center.
- Completed
- Registry status
- 29
- Enrollment target
- 1
- Study location
NCT01238445: Completed study of Bronchiolitis, sponsored by Connecticut Children's Medical Center.
NCT01238445 is a study of Bronchiolitis that has completed, run by Connecticut Children's Medical Center. The registered enrollment target is 29 participants, below the 574-participant average among 12 other Bronchiolitis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01238445, a study of Bronchiolitis, has completed, sponsored by Connecticut Children's Medical Center.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
Bronchiolitis is a significant cause of morbidity and hospitalizations in children, accounting for more than 125,000 hospitalized children per year in the United States. Although treatment is largely supportive, bronchodilator medications such as albuterol are frequently used due to increased pulmonary resistance in this population.2-4 However, despite four decades of clinical trials, the efficacy of albuterol in the treatment of bronchiolitis has yet to be proven. This inconsistency is due in part to the lack of sufficiently sensitive methods for the evaluation of lung function and thus the response to albuterol in infants. Because of the difficulties in evaluating the response to therapy, healthcare providers are forced to rely on their physical examination skills or a clinical scoring system, both of which are highly subjective in this population. The investigators propose to conduct a prospective observational study of healthcare providers to determine the accuracy of clinical assessment as compared to that of pulmonary mechanics in a population of children intubated and mechanically ventilated for bronchiolitis.
Conditions Studied
Study Locations (1)
Connecticut
- Connecticut Children's Medical Center - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2010-11 |
| Est. Completion | 2016-11 |
What the finished NCT01238445 record still lists
NCT01238445 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 574-participant average among 12 other Bronchiolitis trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Bronchiolitis appearing as the primary indexed condition, and to 0 interventions.
NCT01238445 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT01238445 about?
NCT01238445 is a clinical study titled "Assessing Response to Albuterol in Bronchiolitis". Bronchiolitis is a significant cause of morbidity and hospitalizations in children, accounting for more than 125,000 hospitalized children per year in the United States. Although treatment is largely supportive, bronchodilator medications such as albuterol are frequently used due to increased pulmon...
What is the current status of trial NCT01238445?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2010-11. Estimated completion is 2016-11.
What conditions does trial NCT01238445 study?
This clinical trial studies the following conditions: Bronchiolitis.
Who is sponsoring clinical trial NCT01238445?
This trial is sponsored by Connecticut Children's Medical Center, which has 55 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01238445 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bronchiolitis
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Where NCT01238445's enrollment target sits among peer trials
29 13th of 12 the lowest of 12 other Bronchiolitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bronchiolitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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