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NCT06053684 · ClinicalTrials.gov registry record · NA

Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis

A NA study of Bronchiolitis, sponsored by Montefiore Medical Center.

Recruiting
Registry status
NA
Development phase
130
Enrollment target
1
Study location

NCT06053684: Recruiting NA study of Bronchiolitis, sponsored by Montefiore Medical Center.

NCT06053684 is a NA study of Bronchiolitis that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 130 participants, below the 566-participant average among 12 other Bronchiolitis trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06053684, a NA study of Bronchiolitis, is actively recruiting participants, sponsored by Montefiore Medical Center.

RECRUITING
Registry status
NA
Development phase
130 participants
Enrollment target
1
Study location

Study Summary

This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy (including intubation) when compared to using a standard mode of non-invasive ventilation. Neurally-Adjusted Ventilatory Assistance (NAVA) has been shown to result in greater synchrony then the standard mode of non-invasive ventilation. The study team hypothesizes that this improved synchrony can result in important clinical improvements when NAVA is used to treat children with bronchiolitis.

Primary Outcome

RSS is a validated measure of severity in children with bronchiolitis, scored from 0-12 with higher numbers indicating greater severity. If able, baseline scores will be taken before randomization to either treatment arm.

Conditions Studied

Interventions

  • DEVICE Standard Non-Invasive Mechanical Servo Ventilation
  • DEVICE Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation

Study Locations (1)

New York

  • Children's Hospital at Montefiore - The Bronx

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2023-12-18
Est. Completion 2027-03
Phase NA
Montefiore Medical Center

345 total trials

What NCT06053684 shows while recruiting

NCT06053684 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 566-participant average among 12 other Bronchiolitis trials with a reported enrollment target (77% lower).

The record links to 1 condition, with Bronchiolitis appearing as the primary indexed condition, and to 2 interventions - of which Standard Non-Invasive Mechanical Servo Ventilation is the first listed.

NCT06053684 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT06053684 about?

NCT06053684 is a clinical study titled "Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis". This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy (including intubation) when compared to using a standard mode of non-inv...

What is the current status of trial NCT06053684?

This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2023-12-18. Estimated completion is 2027-03.

What conditions does trial NCT06053684 study?

This clinical trial studies the following conditions: Bronchiolitis.

What interventions are being tested in trial NCT06053684?

The interventions under investigation include: Standard Non-Invasive Mechanical Servo Ventilation (DEVICE), Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation (DEVICE).

Who is sponsoring clinical trial NCT06053684?

This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06053684 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Bronchiolitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06053684's enrollment target sits among peer trials

130 9th of 12 higher than 4 of 12 other Bronchiolitis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Bronchiolitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06053684, the US trial registry maintained by the National Library of Medicine. NCT06053684 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.