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NCT01217931 · ClinicalTrials.gov registry record · Phase 2
Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial
A Phase 2 study of Kidney Cancer, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT01217931: Active Phase 2 study of Kidney Cancer, sponsored by M.D. Anderson Cancer Center.
NCT01217931 is a Phase 2 study of Kidney Cancer that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 180 participants, below the 877-participant average among 60 other Kidney Cancer trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01217931, a Phase 2 study of Kidney Cancer, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical research study is to compare 6 different 2-drug "sequences" of everolimus, bevacizumab, or pazopanib to learn how they may affect metastatic kidney cancer. For the 2-drug sequence, participants will receive 1 of these drugs and may start taking another of these drugs after that. Researchers will also study the safety of these 2-drug sequences.
Primary Outcome
Measured from date of randomization to date of second disease progression, 'drop-out' from protocol treatment for any reason or death, associated with each of the six two-agent sequential therapies given in parallel.
Conditions Studied
Interventions
- DRUG Bevacizumab
- DRUG Everolimus
- DRUG Pazopanib
Study Locations (1)
Texas
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2011-01-19 |
| Est. Completion | 2028-01-31 |
| Phase | Phase 2 |
What the registry record for NCT01217931 still lists
NCT01217931 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 877-participant average among 60 other Kidney Cancer trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Kidney Cancer appearing as the primary indexed condition, and to 3 interventions - of which Bevacizumab is the first listed.
NCT01217931 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01217931 about?
NCT01217931 is a clinical study titled "Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial". The goal of this clinical research study is to compare 6 different 2-drug "sequences" of everolimus, bevacizumab, or pazopanib to learn how they may affect metastatic kidney cancer. For the 2-drug sequence, participants will receive 1 of these drugs and may start taking another of these drugs after ...
What is the current status of trial NCT01217931?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 180 participants. The study started on 2011-01-19. Estimated completion is 2028-01-31.
What conditions does trial NCT01217931 study?
This clinical trial studies the following conditions: Kidney Cancer.
What interventions are being tested in trial NCT01217931?
The interventions under investigation include: Bevacizumab (DRUG), Everolimus (DRUG), Pazopanib (DRUG).
Who is sponsoring clinical trial NCT01217931?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01217931 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01217931's enrollment target sits among peer trials
180 17th of 60 higher than 44 of 60 other Kidney Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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