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NCT01184118 · ClinicalTrials.gov registry record · NA
DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?
A NA study, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT01184118: Completed NA study, sponsored by University of Wisconsin, Madison.
NCT01184118 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01184118, a NA study, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
This study is being conducted to find out if the use of inhaled corticosteroids has an affect on upper airway (UAW) collapsibility and sleep apnea risk. An inhaled corticosteroid is a common asthma controller medication like Flovent. Sleep apnea or sleep deprived breathing (SDB) is when someone stops breathing for a short period of time during sleep. For some reason, people with asthma have more sleep apnea and upper airway (UAW) collapsibility (weakness) than the general population. There are many possible reasons for this and one might be related to the use of inhaled corticosteroids. The overall hypothesis of this study is to determine whether inhaled fluticasone propionate (FP) increases UAW collapsibility and to assess tongue (genioglossus muscle) dysfunction as a potential underlying mechanism.
Primary Outcome
Upper airway (UAW) collapsibility, as measured by critical closing pressure (Pcrit), defined as the maximum nasal pressure at which the UAW occludes. Subjects were divided into 3 subgroups: improved (more negative Pcrit), unchanged, or worsened (less negative Pcrit).
Interventions
- DRUG FP 220 mcg 2 puffs BID
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2009-03 |
| Est. Completion | 2011-02 |
| Phase | NA |
What the finished NCT01184118 record still lists
NCT01184118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which FP 220 mcg 2 puffs BID is the first listed.
NCT01184118 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01184118 about?
NCT01184118 is a clinical study titled "DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?". This study is being conducted to find out if the use of inhaled corticosteroids has an affect on upper airway (UAW) collapsibility and sleep apnea risk. An inhaled corticosteroid is a common asthma controller medication like Flovent. Sleep apnea or sleep deprived breathing (SDB) is when someone stop...
What is the current status of trial NCT01184118?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2009-03. Estimated completion is 2011-02.
What interventions are being tested in trial NCT01184118?
The interventions under investigation include: FP 220 mcg 2 puffs BID (DRUG).
Who is sponsoring clinical trial NCT01184118?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01184118's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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