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NCT01136733 · ClinicalTrials.gov registry record · Phase 1

A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment

A Phase 1 study of Metastatic Renal Cell Carcinoma, sponsored by Eisai.

Completed
Registry status
Phase 1
Development phase
173
Enrollment target
20
Study locations

NCT01136733 is a Phase 1 study of Metastatic Renal Cell Carcinoma that has completed, run by Eisai. The registered enrollment target is 173 participants, above the 139-participant average among 37 other Metastatic Renal Cell Carcinoma trials with a reported enrollment target (24% higher). The trial reports 20 study locations across 13 states.

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The verdict

NCT01136733, a Phase 1 study of Metastatic Renal Cell Carcinoma, has completed, sponsored by Eisai.

COMPLETED
Registry status
Phase 1
Development phase
173 participants
Enrollment target
20
Study locations

Study Summary

This is an open-label, multicenter, Phase 1b/2 study of lenvatinib alone and in combination with everolimus in subjects with unresectable advanced or metastatic renal cell carcinoma following one prior VEGF-targeted treatment.

Interventions

  • DRUG Everolimus
  • DRUG Lenvatinib

Study Locations (20)

Other

  • - Brno
  • - Olomouc
  • - Prague
  • - Gdansk
  • - Lodz
  • - Szczecin

California

  • - Orange
  • - San Diego

Maryland

  • - Annapolis
  • - Bethesda

Arizona

  • - Tucson

Florida

  • - Tampa

Illinois

  • - Joliet

Kentucky

  • - Louisville

Massachusetts

  • - Boston

Trial Details

FieldValue
Enrollment Target 173 participants
Start Date 2010-08-05
Est. Completion 2018-02-08
Phase Phase 1

Sponsor

Eisai

287 total trials

What the Registry Record Tells You About NCT01136733

The ClinicalTrials.gov registry entry for NCT01136733 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 173 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 139-participant average among 37 other Metastatic Renal Cell Carcinoma trials with a reported enrollment target (24% higher). The listed sponsor is Eisai, which has 287 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Metastatic Renal Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Everolimus is the first listed.

NCT01136733 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Other, California, Maryland.

Frequently Asked Questions

What is clinical trial NCT01136733 about?

NCT01136733 is a clinical study titled "A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment". This is an open-label, multicenter, Phase 1b/2 study of lenvatinib alone and in combination with everolimus in subjects with unresectable advanced or metastatic renal cell carcinoma following one prior VEGF-targeted treatment.

What is the current status of trial NCT01136733?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 173 participants. The study started on 2010-08-05. Estimated completion is 2018-02-08.

What conditions does trial NCT01136733 study?

This clinical trial studies the following conditions: Metastatic Renal Cell Carcinoma.

What interventions are being tested in trial NCT01136733?

The interventions under investigation include: Everolimus (DRUG), Lenvatinib (DRUG).

Who is sponsoring clinical trial NCT01136733?

This trial is sponsored by Eisai, which has 287 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01136733 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.