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NCT01120275 · ClinicalTrials.gov registry record · Phase 2

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 2
Development phase
36
Enrollment target

NCT01120275: Clinical Trial Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT01120275 is a Phase 2 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 36 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01120275, a Phase 2 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 2
Development phase
36 participants
Enrollment target

Study Summary

This phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with stage IV melanoma. Gamma-secretase/Notch signalling pathway inhibitor RO4929097 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG gamma-secretase/Notch signalling pathway inhibitor RO4929097

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2010-10
Est. Completion 2015-08
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01120275

The ClinicalTrials.gov registry entry for NCT01120275 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which laboratory biomarker analysis is the first listed.

NCT01120275 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01120275 about?

NCT01120275 is a clinical study titled "Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma". This phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with stage IV melanoma. Gamma-secretase/Notch signalling pathway inhibitor RO4929097 may stop the growth of tumor cells by blocking some of the enzymes needed for cell gro...

What is the current status of trial NCT01120275?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2010-10. Estimated completion is 2015-08.

What interventions are being tested in trial NCT01120275?

The interventions under investigation include: laboratory biomarker analysis (OTHER), gamma-secretase/Notch signalling pathway inhibitor RO4929097 (DRUG).

Who is sponsoring clinical trial NCT01120275?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.