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NCT01114776 · ClinicalTrials.gov registry record
Multi-Center Study of Iron Overload: Pilot Study
A clinical trial of Sickle Cell Disease and Thalassemia, sponsored by UCSF Benioff Children's Hospital Oakland.
- Completed
- Registry status
- 20
- Enrollment target
- 3
- Study locations
NCT01114776 is a study of Sickle Cell Disease and Thalassemia that has completed, run by UCSF Benioff Children's Hospital Oakland. The registered enrollment target is 20 participants, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 2 states.
The verdict
NCT01114776, a study of Sickle Cell Disease and Thalassemia, has completed, sponsored by UCSF Benioff Children's Hospital Oakland.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to initiate pilot studies to demonstrate that a sufficient number of iron-overloaded thalassemia, SCD and DBA populations with similar duration of chronic transfusion, and age at start of transfusions would be available for a confirmatory study and to validate that proposed multicenter MRI and biochemical studies can be completed. The study will examine the hypothesis that a chronic inflammatory state in Sickle Cell Disease (SCD) leads to hepcidin- and cytokine-mediated iron withholding within the RES (reticuloendothelial system), lower plasma NTBI (non transferrin bound iron) levels, less distribution of iron to the heart in SCD.
Conditions Studied
Study Locations (3)
Other
- Universitätsklinikum Hamburg-Eppendorf - Hamburg-Eppendorf
- UCL Cancer Institute - London
California
- Children's Hospital & Research Center Oakland - Oakland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-11-01 |
| Est. Completion | 2013-09-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01114776
The ClinicalTrials.gov registry entry for NCT01114776 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (93% lower). The listed sponsor is UCSF Benioff Children's Hospital Oakland, which has 52 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Sickle Cell Disease appearing as the primary indexed condition, and to 0 interventions.
NCT01114776 reports 3 study locations spanning 2 distinct geographic areas - top geographies include Other, California.
Frequently Asked Questions
What is clinical trial NCT01114776 about?
NCT01114776 is a clinical study titled "Multi-Center Study of Iron Overload: Pilot Study". The purpose of this study is to initiate pilot studies to demonstrate that a sufficient number of iron-overloaded thalassemia, SCD and DBA populations with similar duration of chronic transfusion, and age at start of transfusions would be available for a confirmatory study and to validate that propo...
What is the current status of trial NCT01114776?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2009-11-01. Estimated completion is 2013-09-30.
What conditions does trial NCT01114776 study?
This clinical trial studies the following conditions: Sickle Cell Disease, Thalassemia, Diamond-Blackfan Anemia.
Who is sponsoring clinical trial NCT01114776?
This trial is sponsored by UCSF Benioff Children's Hospital Oakland, which has 52 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01114776 being conducted?
This trial has 3 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.