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NCT01088048 · ClinicalTrials.gov registry record · Phase 1

Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia

A Phase 1 study, sponsored by Gilead Sciences.

Completed
Registry status
Phase 1
Development phase
241
Enrollment target

NCT01088048 is a Phase 1 study that has completed, run by Gilead Sciences. The registered enrollment target is 241 participants.

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The verdict

NCT01088048, a Phase 1 study, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 1
Development phase
241 participants
Enrollment target

Study Summary

The primary objective of the study is to evaluate the safety of idelalisib in combination with an anti-CD20 monoclonal antibody (mAb), a chemotherapeutic agent, a mammalian target of rapamycin (mTOR) inhibitor, a protease inhibitor, an antiangiogenic agent, and/or an immunomodulatory agent in participants with relapsed or refractory indolent B-cell non-Hodgkin lymphoma (NHL), mantle cell lymphoma (MCL), or chronic lymphocytic leukemia (CLL).

Interventions

  • DRUG Fludarabine
  • DRUG Rituximab
  • DRUG Bendamustine
  • DRUG Idelalisib
  • DRUG Ofatumumab

Trial Details

FieldValue
Enrollment Target 241 participants
Start Date 2010-03-25
Est. Completion 2015-04-28
Phase Phase 1

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT01088048

The ClinicalTrials.gov registry entry for NCT01088048 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 241 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Fludarabine is the first listed.

NCT01088048 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01088048 about?

NCT01088048 is a clinical study titled "Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia". The primary objective of the study is to evaluate the safety of idelalisib in combination with an anti-CD20 monoclonal antibody (mAb), a chemotherapeutic agent, a mammalian target of rapamycin (mTOR) inhibitor, a protease inhibitor, an antiangiogenic agent, and/or an immunomodulatory agent in partic...

What is the current status of trial NCT01088048?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 241 participants. The study started on 2010-03-25. Estimated completion is 2015-04-28.

What interventions are being tested in trial NCT01088048?

The interventions under investigation include: Fludarabine (DRUG), Rituximab (DRUG), Bendamustine (DRUG), Idelalisib (DRUG), Ofatumumab (DRUG).

Who is sponsoring clinical trial NCT01088048?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.