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NCT01026987 · ClinicalTrials.gov registry record · Phase 1
Granulocyte Colony-stimulating Factor (G-CSF) Plus or Minus AMD3100 for Engraftment Post Allogeneic Transplant
A Phase 1 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT01026987: Completed Phase 1 study, sponsored by Washington University School of Medicine.
NCT01026987 is a Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 29 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01026987, a Phase 1 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
Patients who have not had adequate blood count recovery post related or unrelated stem cell transplant will be given a "boost" of T-cell depleted, enriched stem cells to hopefully improve their blood counts.
Primary Outcome
For recipients with ANC \< 500 or growth factor support dependent at study entry, Time to neutrophil improvement is measured from the date of CD34+ selected, T-Cell depleted infusion to the first of 3 consecutive measurements of neutrophil count \> 500/μl without growth factor support for \>7 days prior. RBC transfusion engraftment - independence from RBCs without growth factors.
Interventions
- DRUG G-CSF
- PROCEDURE Leukapheresis
- DRUG AMD3100
- PROCEDURE Stem Cell Infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2010-04-29 |
| Est. Completion | 2016-06-08 |
| Phase | Phase 1 |
What the finished NCT01026987 record still lists
NCT01026987 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 4 interventions - of which G-CSF is the first listed.
NCT01026987 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01026987 about?
NCT01026987 is a clinical study titled "Granulocyte Colony-stimulating Factor (G-CSF) Plus or Minus AMD3100 for Engraftment Post Allogeneic Transplant". Patients who have not had adequate blood count recovery post related or unrelated stem cell transplant will be given a "boost" of T-cell depleted, enriched stem cells to hopefully improve their blood counts.
What is the current status of trial NCT01026987?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2010-04-29. Estimated completion is 2016-06-08.
What interventions are being tested in trial NCT01026987?
The interventions under investigation include: G-CSF (DRUG), Leukapheresis (PROCEDURE), AMD3100 (DRUG), Stem Cell Infusion (PROCEDURE).
Who is sponsoring clinical trial NCT01026987?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01026987's enrollment target sits among peer trials
29 1440th of 2000 higher than 554 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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