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COMPLETED Phase 1

A Study Of PF-04449913 In Select Hematologic Malignancies

NCT00953758 · View on ClinicalTrials.gov ↗

Study Summary

This study examines the effect of a small molecule inhibitor to the Sonic Hedgehog pathway on select hematologic malignancies.

Conditions Studied

Interventions

  • DRUG PF-04449913

Study Locations (6)

California

  • UCSD Medical Center - La Jolla — La Jolla
  • Moores UCSD Cancer Center — La Jolla
  • UCSD Medical Center - Hillcrest — San Diego

Texas

  • The University of Texas M.D. Anderson Cancer Center — Houston

Washington

  • University of Washington Medical Center, Seattle Cancer Care Alliance — Seattle

Other

  • U.O. di Ematologia — Bologna

Trial Details

FieldValue
Enrollment Target 47 participants
Start Date 2010-03-03
Est. Completion 2013-02-27
Phase Phase 1

Sponsor

Pfizer

769 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00953758

The ClinicalTrials.gov registry entry for NCT00953758 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 47 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hematologic Malignancies appearing as the primary indexed condition, and to 1 intervention — of which PF-04449913 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00953758 reports 6 study locations spanning 4 distinct geographic areas — top geographies include California, Texas, Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00953758 about?

NCT00953758 is a clinical study titled "A Study Of PF-04449913 In Select Hematologic Malignancies". This study examines the effect of a small molecule inhibitor to the Sonic Hedgehog pathway on select hematologic malignancies.

What is the current status of trial NCT00953758?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2010-03-03. Estimated completion is 2013-02-27.

What conditions does trial NCT00953758 study?

This clinical trial studies the following conditions: Hematologic Malignancies. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00953758?

The interventions under investigation include: PF-04449913 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00953758?

This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00953758 being conducted?

This trial has 6 study locations across California, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial