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NCT00935623 · ClinicalTrials.gov registry record · Phase 1
Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans
A Phase 1 study, sponsored by U.S. Army Medical Research and Development Command.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT00935623: Completed Phase 1 study, sponsored by U.S. Army Medical Research and Development Command.
NCT00935623 is a Phase 1 study that has completed, run by U.S. Army Medical Research and Development Command. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00935623, a Phase 1 study, has completed, sponsored by U.S. Army Medical Research and Development Command.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this study is to demonstrate that volunteers can be safely and reproducibly infected with Plasmodium vivax (P. vivax) by the bites of experimentally infected Anopheles dirus (An. dirus) mosquitoes carrying P. vivax sporozoites in their salivary glands.
Interventions
- BIOLOGICAL Malaria Challenge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2009-04-21 |
| Est. Completion | 2011-09 |
| Phase | Phase 1 |
What the finished NCT00935623 record still lists
NCT00935623 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 1 intervention - of which Malaria Challenge is the first listed.
NCT00935623 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00935623 about?
NCT00935623 is a clinical study titled "Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans". The purpose of this study is to demonstrate that volunteers can be safely and reproducibly infected with Plasmodium vivax (P. vivax) by the bites of experimentally infected Anopheles dirus (An. dirus) mosquitoes carrying P. vivax sporozoites in their salivary glands.
What is the current status of trial NCT00935623?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2009-04-21. Estimated completion is 2011-09.
What interventions are being tested in trial NCT00935623?
The interventions under investigation include: Malaria Challenge (BIOLOGICAL).
Who is sponsoring clinical trial NCT00935623?
This trial is sponsored by U.S. Army Medical Research and Development Command, which has 77 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00935623's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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