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NCT00934024 · ClinicalTrials.gov registry record · NA

Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers

A NA study, sponsored by Medical University of South Carolina.

Completed
Registry status
NA
Development phase
21
Enrollment target

NCT00934024: Completed NA study, sponsored by Medical University of South Carolina.

NCT00934024 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00934024, a NA study, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
NA
Development phase
21 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the impact of varenicline treatment on cue induced craving to smoking using brain imaging. The investigators hypothesize that participants will report reduced urges to smoke and will have less activation in parts of the brain associated with craving.

Primary Outcome

Change in Post-resist task craving between Scan 1, pre-medication, and Scan 2, post- medication, as measured on a 0-10 Likert scale. The Within Sessions Rating scale (Range 0-10) measures craving with 0 indicating Not at All and 10 indicating Extremely. Change scores were calculate by subtracting the craving score immediately following the pre-medication scan from the craving score immediately following the post-medication scan.

Interventions

  • DRUG varenicline

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2009-04
Est. Completion 2012-01
Phase NA

What the finished NCT00934024 record still lists

NCT00934024 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which varenicline is the first listed.

NCT00934024 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00934024 about?

NCT00934024 is a clinical study titled "Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers". The purpose of this study is to evaluate the impact of varenicline treatment on cue induced craving to smoking using brain imaging. The investigators hypothesize that participants will report reduced urges to smoke and will have less activation in parts of the brain associated with craving.

What is the current status of trial NCT00934024?

This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2009-04. Estimated completion is 2012-01.

What interventions are being tested in trial NCT00934024?

The interventions under investigation include: varenicline (DRUG).

Who is sponsoring clinical trial NCT00934024?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00934024's enrollment target sits among peer trials

21 1762nd of 2000 higher than 233 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00934024, the US trial registry maintained by the National Library of Medicine. NCT00934024 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.